Demographic and clinicopathological profile of oral squamous cell carcinoma patients of North India: A retrospective institutional study

Tandon, Aanchal; Bordoloi, Bharadwaj; Jaiswal, Rakesh; Srivastava, Abhinav; Singh, Rajeev; Shafique, Uzma

doi:10.4103/srmjrds.srmjrds_21_18

Cited by 29 publications

(18 citation statements)

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“…We found a definitive male predilection which is similar to previous studies [39]. It was found that the maximum number of cases were aged 50 years and above and the majority (45%) had a Hb value between 9-11 mg/dl.…”

Section: Resultssupporting

confidence: 91%

Analysis of Hemoglobin Levels among Oral Cancer Patients: An Institutional Study

Desai

Ramani

Pandiar

2021

JPRI

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Background: Oral squamous cell carcinoma (OSCC) is one of the most common types of cancer worldwide. It is estimated that approximately half of all the tumors affecting the head and neck region commonly affect the oral cavity. Premalignant lesions can manifest as leukoplakia, erythroplakia, keratosis or even oral candidiasis. Hemoglobin (Hb) is a protein contained in the red blood cells of the body and plays an important role in delivery of oxygen to the tissues. A sufficient level of Hemoglobin is required to maintain oxygenation of the tissues. Anemia is defined as a reduction in hemoglobin levels below the lower limit pertaining to a particular age group. Treating anemia by increasing the levels of hemoglobin has proven to increase the quality of life of cancer patients. The aim of the present study is to analyze the Hb level in OSCC patients attending our institution. Materials and Methods: The present retrospective institutional study was conducted after obtaining ethical clearance from the Institutional Ethical Approval Board to access patient records and data. A total of 5, 00,000 case sheets were analyzed from June 2019 to February 2021. Suitable inclusion and exclusion criteria were applied and case sheets were shortlisted. The data were entered in MS Excel spreadsheet and further statistical analysis was carried out using SPSS. All results were displayed as graphs and pie charts. Results: 64 cases of OSCC were included in the present study with a male predominance. 45% of the study population had a level between 9-11 mg/dl. 60.3% of the population belonged to the age group of 50 and above. Conclusion: Anemia in cancer can be precipitated due to various factors. It can be caused or exacerbated by the cancer itself due to immunosuppression or due to chemotherapy. Anemia can also be pre existing due to underlying conditions. It was found that hemoglobin levels are found to be higher in males and higher in ages 50+ when compared to ages 30-40. Low levels of hemoglobin and anemic conditions in oral cancer patients can cause excessive fatigue and can significantly affect quality of life and hence, hemoglobin therapy is widely administered to oral cancer patients.

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Section: Resultssupporting

confidence: 91%

Analysis of Hemoglobin Levels among Oral Cancer Patients: An Institutional Study

Desai

Ramani

Pandiar

2021

JPRI

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“…This is in accordance with several other studies. 3,7,9,10 Men predominated over women with male to female ratio of 5:1. Our findings are similar to several other studies.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…2 Most common risk factor is tobacco usage. [3][4][5] In India, rampant usage of various forms of smokeless tobacco like khaini, gutkha is the leading risk factor, others being alcohol consumption, low socioeconomic status, and lack of oral hygiene.This retrospective study was conducted in a tertiary care hospital and medical college and hospital of ESIC, which is a social security system aimed at the labor class population of India with a budget of 80,000 crore INR (US $11 billion). This scheme is one of the biggest social security providers in the world and is designed to provide socioeconomic protection to employees in the organized sector, with the provision of medical benefits being its major strength.…”

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confidence: 99%

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Clinical Profile and Management of Oral Cancer; Is Tobacco Ban the Need of the Hour? An ESIC Tertiary Care Hospital Experience

Kharkwal¹,

Sarkar²,

Boban³

et al. 2023

International Journal of Head and Neck Surgery

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In this scheme, the employee's contribution rate is 0.75% of the wages, and that of the employer's is 3.25% of the wages paid/payable in respect of the employees in every wage period, and though the contributions are based on the workers IntroductIonOral cancer is one of the commonest cancers in India, and as per the Globocan 2020 data, it is the most common cancer among Indian males and the second most common cancer in both sexes. 1 Though curable if detected in early stages and also easily accessible by virtue of site for examination, both by a patient as well as healthcare worker, most patients reach in locally advanced and late stages, leading to complex management protocols, poorer treatment outcomes, and increasing health care burden. 2 Most common risk factor is tobacco usage. [3][4][5] In India, rampant usage of various forms of smokeless tobacco like khaini, gutkha is the leading risk factor, others being alcohol consumption, low socioeconomic status, and lack of oral hygiene.This retrospective study was conducted in a tertiary care hospital and medical college and hospital of ESIC, which is a social security system aimed at the labor class population of India with a budget of 80,000 crore INR (US $11 billion). This scheme is one of the biggest social security providers in the world and is designed to provide socioeconomic protection to employees in the organized sector, with the provision of medical benefits being its major strength. As the monthly wage ceiling for coverage of an employee

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“…A study done by Bordoloi et al . [ 4 ] from northern India suggested that delay in diagnosis of OSCC in most of the cases (66.32%) was around 2–6 months. This can be caused by factors such as patients' negligence due to lack of awareness, illiteracy, poverty, and home remedies.…”

Section: Discussionmentioning

confidence: 99%

Ponderous pleomorphic adenoma of parotid obscuring a grievous tumor of the head and neck: A rare case report

Dikhit

Roy

Srivastava

et al. 2021

Int J App Basic Med Res

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We present a rare case of simultaneous occurrence of pleomorphic adenoma of the left parotid gland and squamous cell carcinoma (SCC) of left buccal mucosa in a 59-year-old patient. The synchronous occurrence of these two entities has not been reported in the literature. A PubMed database search did not yield any results for search words involving “Oral Cancer,” “Synchronous Oral Cancer and Pleomorphic Adenoma of Parotid gland” and “Oral SCC and Pleomorphic Adenoma of Parotid gland.” Furthermore, synchronous development of these two tumors may give rise to diagnostic and ma?nagement conundrums as the parotid growth may be considered to be a nodal metastasis.

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Demographic and clinicopathological profile of oral squamous cell carcinoma patients of North India: A retrospective institutional study

Cited by 29 publications

References 0 publications

Analysis of Hemoglobin Levels among Oral Cancer Patients: An Institutional Study

Analysis of Hemoglobin Levels among Oral Cancer Patients: An Institutional Study

Clinical Profile and Management of Oral Cancer; Is Tobacco Ban the Need of the Hour? An ESIC Tertiary Care Hospital Experience

Ponderous pleomorphic adenoma of parotid obscuring a grievous tumor of the head and neck: A rare case report

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