Demographic and clinical features of suspected dengue and dengue haemorrhagic fever in the Northern Province of Sri Lanka, a region afflicted by an internal conflict for more than 30 years—a retrospective analysis

Murugananthan, Kalamathy; Kandasamy, Mohanakrishnan; Rajeshkannan, Nadarajah; Noordeen, F.

doi:10.1016/j.ijid.2014.04.014

Cited by 20 publications

(20 citation statements)

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“…15 Male to female ratio of 1.82:1 was reported in another study. 13 However, approximately equal number of affected females 550 (50.70%) and males 535 (49.30%) were reported by Murugananthan K et al 16 Higher seropositivity in males might be because of increased exposure at work places or outdoor activities.…”

Section: Gender Wise Distributionmentioning

confidence: 95%

Dengue infection in central India: a 5 years study at a tertiary care hospital

2017

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Background: Dengue is one of the most important mosquito borne viral disease with wide spectrum of clinical presentation and often with unpredictable clinical evolution and outcome. Approximately 50 million infections occur annually world-wide, but what’s the real size of the problem in India? Nobody truly knows...!! Present study was carried out to determine seropositivity, clinical profile and seasonal variation of dengue infection in central India.Methods: Study was carried out from January 2012 to December 2016. Blood samples were collected from 15,606 patients with dengue like clinical illness and serum was separated. All the samples were subjected to IgM antibody detection by dengue MAC ELISA.Results: Prevalence of dengue in dengue suspected cases was found to be 24.49% (3,822/15,606). Maximum number of positive cases, 1,548 (40.50%) were in the age group of 0-10 years. Males (60.83%) were affected more than females (39.17%). Peak was observed in the months of August, September, October and November. Common presenting features were fever followed by myalgia, arthralgia, headache and bleeding manifestations. Significant drop in platelet count was observed in patients with dengue shock syndrome and dengue haemorrhagic fever.Conclusions: Number of dengue cases in central India are on increase and continued surveillance is essential to determine epidemiological and seasonal trend.

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Section: Gender Wise Distributionmentioning

confidence: 95%

Dengue infection in central India: a 5 years study at a tertiary care hospital

2017

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“…Generally clinical featured in this study consistent with other report. 25 In conclusion, we have presented the profile of dengue cases of two hospitals in Samarinda and Manado. Most of the cases have previously been exposed to dengue infection likewise in children.…”

Section: Discussionmentioning

confidence: 93%

Clinical and virological profile of Dengue cases: a study in Samarinda and Manado

Herman¹

2018

hsji

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Latar Belakang: Infeksi virus dengue masih merupakan masalah kesehatan di Indonesia. Studi inidilakukan di Samarinda dan Manado, tujuannya untuk mendapatkan profil klinis dan virologi daripenderita anak dan dewasa di Wilayah Tengah Indonesia. Metode: Ini merupakan studi deskriptif, kasus infeksi dengue didapat dari Rumah Sakit Umum diSamarinda dan Manado pada tahun 2012-2013. Sampel darah berasal dari penderita infeksi dengue yangdirawat di Bagian Anak dan Penyakit Dalam. Konfirmasi infeksi dengue dilakukan dengan pemeriksaannested RT-PCR, deteksi antibodi Ig M dan Ig G dilakukan dengan capture ELISA untuk menentukankemungkian infeksi dengue maupun jenis infeksi. Definisi infeksi primer dan sekunder berdasarkankeberadaan antibodi Ig G. Profil klinis dijabarkan berdasarkan sampel terkonfirmasi infeksi dengue. Hasil: Sebanyak 485 penderita ikut dalam penelitian ini, 40 % diantaranya terkonfirmasi infeksi dengue.Tiga puluh lima persen diantaranya kemungkinan terinfeksi virus dengue berdasarkan antibodi. Secaraumum virus dengue serotipe 2 (DENV-2) paling banyak ditemukan pada penelitian ini, selain itu ditemukanjuga infeksi campuran (2 serotip berbeda) di Samarinda. Sebanyak 72 % dari kasus terkonfirmasi infeksidengue merupakan infeksi sekunder, demikian juga pada penderita anak. Demam, sakit kepala, mual dannyeri pada perut merupakan profil klinis yang paling banyak ditemukan. Kesimpulan: Keempat serotip virus dengue ditemukan dari kasus-kasus di RS Abdul Wahab Sjahranie,Samarinda dan RS. Prof. Dr. R.D. Kandou, Manado, secara umum DENV-2 merupakan yang palingdominan. Kebanyakan penderita sudah pernah terinfeksi dengue sebelumnya demikian juga penderita anak.(Health Science Journal of Indonesia 2018;9(2):76-81) Kata kunci: Infeksi dengue, Samarinda, Manado Abstract Background: Dengue infection is one of public health problem in Indonesia. This study was conductedSamarinda and Manado, which aimed to report of clinical and virological profile among hospitalizedchildren and adult dengue patients in central region of Indonesia. Method: This was a descriptive study, dengue cases were collected in general hospital in Samarinda andManado from 2012 to 2013. Patient with dengue infection when admitted from pediatric and internaldiseases ward included in this study. Sera were collected and nested RT-PCR was performed to confirmeddengue virus. Dengue Ig M/Ig G antibodies detected using capture ELISA for probability of dengueinfection. Definition of primary and secondary infection was based on existence of IgG antibodies. Clinicalprofile was described base on confirmed results. Results: Four hundred and eighty five cases were included; 40 % were confirmed dengue infection and35 % were probably dengue infection based on antibody. Dengue serotype 2 was dominant from bothsites, furthermore mixed infections were found in Samarinda. Seventy two percent of confirmed caseswere secondary infection, likewise in children. Fever, headache, nausea and abdominal pain were the mostcommon signs and symptoms of confirmed cases. Conclusion: All four serotype of DENV found cases in Abdul Wahab Sjahranie Hospital, Samarindaand Prof. Dr. R.D. Kandou Hospital, Manado, generally DENV-2 were dominant. Most of the cases havebeen exposed to dengue infection previously similarly in children. (Health Science Journal of Indonesia2018;9(2):76-81) Keywords: Dengue infection, Samarinda, Manado

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“…This statement is collaborated by the results of several study (Conroy et al, 2015;Devaleenal et al, 2015;Murugananthan et al, 2014;Phung et al, 2015;Vasquez-Velasquez et al, 2015), which stated that the adverse effects of the phenomenon of urbanization form the ideal environment for the aedes aegypti mosquito as a carrier vector for breeding in the urban settlement area .…”

Section: Introductionmentioning

confidence: 92%

Relationship Between Urbanization and Dengue Hemorrhagic Fever Incidence in Semarang City

Pratama

Rahayu

2016

Geoplanning: Journal of Geomatics and Planning

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Demographic and clinical features of suspected dengue and dengue haemorrhagic fever in the Northern Province of Sri Lanka, a region afflicted by an internal conflict for more than 30 years—a retrospective analysis

Abstract: The absence of laboratory diagnosis and poor notification to the Epidemiology Unit were the major drawbacks noted.

Cited by 20 publications

References 12 publications

Dengue infection in central India: a 5 years study at a tertiary care hospital

Dengue infection in central India: a 5 years study at a tertiary care hospital

Clinical and virological profile of Dengue cases: a study in Samarinda and Manado

Relationship Between Urbanization and Dengue Hemorrhagic Fever Incidence in Semarang City

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