Dementia infantilis with cortical dysrhythmia

Kennedy, Alexander; Hill, Dave

doi:10.1136/adc.17.91.122

Cited by 16 publications

(2 citation statements)

References 11 publications

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“…However, there have also been authors who aimed at diminishing the importance of CSWS in the development of cognitive deficits [9]. The first pioneering report that pointed out the connection between continuous EEG paroxysmal abnormalities (spike and wave complexes) and the presence of cognitive disorders should be attributed to Kennedy and Hill, who in 1942 described a child affected by "dementia dysrhythmica infantum" [10]. Between the 1970s and 1980s, Tassinari et al described, in a very detailed and modern way, the electroclinical entity characterized by an EEG with diffuse spikes and waves lasting for at least 85% of slow sleep, clinically associated with Children 2024, 11, 169 2 of 38 cognitive decline, seizures, and motor impairment [11,12].…”

Section: Introductionmentioning

confidence: 99%

Continuous Spike–Waves during Slow Sleep Today: An Update

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Visconti

2024

Children

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In the context of childhood epilepsy, the concept of continuous spike–waves during slow sleep (CSWS) includes several childhood-onset heterogeneous conditions that share electroencephalograms (EEGs) characterized by a high frequency of paroxysmal abnormalities during sleep, which have negative effects on the cognitive development and behavior of the child. These negative effects may have the characteristics of a clear regression or of a slowdown in development. Seizures are very often present, but not constantly. The above makes it clear why CSWS have been included in epileptic encephalopathies, in which, by definition, frequent EEG paroxysmal abnormalities have an unfavorable impact on cognitive functions, including socio-communicative skills, causing autistic features, even regardless of the presence of clinically overt seizures. Although several decades have passed since the original descriptions of the electroclinical condition of CSWS, there are still many areas that are little-known and deserve to be further studied, including the EEG diagnostic criteria, the most effective electrophysiological parameter for monitoring the role of the thalamus in CSWS pathogenesis, its long-term evolution, the nosographic location of Landau–Kleffner syndrome, standardized neuropsychological and behavioral assessments, and pharmacological and non-pharmacological therapies.

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Section: Introductionmentioning

confidence: 99%

Continuous Spike–Waves during Slow Sleep Today: An Update

Posar,

Visconti

2024

Children

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“…a) The first literature report of a condition with electroencephalogram (EEG) continuous paroxysmal abnormalities during sleep associated with cognitive impairment probably dates back to the 1942, when Kennedy and Hill described in a child the clinical picture of “dementia dysrhythmica infantum.” 2 In the following decades Tassinari et al defined this nosographic entity in a much more detailed and modern way, describing the EEG pattern characterized by diffuse spike-and-waves occupying at least 85% of the slow sleep duration, associated with neuropsychological deterioration, motor impairment (ataxia, dyspraxia, etc. ), and focal or apparently generalized seizures.…”

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confidence: 99%