Demência com corpúsculos de Lewy: uma entidade distinta com tratamento específico?

Tatsch, Mariana; Nitrini, Ricardo; Neto, Mario Rodrigues Louzã

doi:10.1590/s1516-44462002000300010

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…Estados degenerativos do sistema nervoso central podem estar relacionados à demência, alucinações e outras alterações na percepção visual (12)(13)(14) . Dessa forma a maioria dos autores a descrevem como uma situação na qual os indivíduos experimentam alucinações visuais complexas, na ausência de doença psiquiátrica ou alteração da consciência (15) .…”

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Síndrome de Charles Bonnet: alucinações visuais em pacientes com doenças oculares - Relato de caso

Cortizo¹,

Rosa²,

Soriano³

et al. 2005

Arq. Bras. Oftalmol.

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In this article the authors report two cases of Charles Bonnet syndrome, defined as complex visual hallucinations in patients with low vision, and the patient is aware of the unreal nature of the phenomenon. A great number of cases is misdiagnosed due to lack of direct questioning by the physician. Since the emotional distress caused by this disease, the knowledge of its symptoms is essential in the management of these patients.

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Section: Discussionunclassified

Síndrome de Charles Bonnet: alucinações visuais em pacientes com doenças oculares - Relato de caso

Cortizo¹,

Rosa²,

Soriano³

et al. 2005

Arq. Bras. Oftalmol.

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Plasma butyrylcholinesterase activity: a possible biomarker for differential diagnosis between Alzheimer's disease and dementia with Lewy bodies?

Josviak

Batistela

Souza

et al. 2017

International Journal of Neuroscience

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Butyrylcholinesterase (BChE) is an enzyme encoded by BCHE gene, responsible for secondary hydrolysis of the acetylcholine. K and -116A BCHE variants were associated with decrease in plasma BChE activity, and their influence has been investigated in diseases with a cholinergic deficit such as Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). In order to check the influence of BCHE genetic variants on enzymatic activity, all patients and controls were genotyped for K and -116A variants. We found lower plasma BChE activity in DLB patients compared to elderly controls and to AD independent of the presence of K or -116A variants. Our results suggest that the reduction of total plasma BChE activity is probably associated with a feedback mechanism and provides a future perspective of using this enzyme as a possible plasmatic marker for differential diagnosis between AD and DLB.

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Demência com corpúsculos de Lewy: uma entidade distinta com tratamento específico?

Cited by 2 publications

References 14 publications

Síndrome de Charles Bonnet: alucinações visuais em pacientes com doenças oculares - Relato de caso

Síndrome de Charles Bonnet: alucinações visuais em pacientes com doenças oculares - Relato de caso

Plasma butyrylcholinesterase activity: a possible biomarker for differential diagnosis between Alzheimer's disease and dementia with Lewy bodies?

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