Demand Oxygen Delivery for Patients with Restrictive Lung Disease

Carter, Rick; Tashkin, Donald P.; Djahed, Benham; Hathaway, Eilish; Nicotra, M. Brooke; Tiep, Brian

doi:10.1378/chest.96.6.1307

Cited by 17 publications

(14 citation statements)

References 11 publications

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“…However, there was no explanation of how these settings were derived (a common trend). This relationship between PF settings and CF was further explored by Carter et al, 20 who compared COPD patient oxygenation using equivalent flow settings of CF and a demand flow device. At rest, a PF setting of 1 was found to be equivalent to CF at 1 L/min (S pO 2 ), with an oxygen-conserving ratio of 4.6.…”

Section: Discussionmentioning

confidence: 99%

Effect of the Anatomic Reservoir on Low-Flow Oxygen Delivery Via Nasal Cannula: Constant Flow Versus Pulse Flow With Portable Oxygen Concentrator

Zhou

Chatburn

2014

Respir Care

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BACKGROUND: The F IO 2 for a nasal cannula with constant flow (CF) depends on the anatomic reservoir (AR), which is affected by changes in frequency and end-expiratory flow. Conversely, pulse flow (PF) devices do not require the AR. The purpose of this study was to compare the F IO 2 delivered by a nasal cannula supplied by CF via oxygen tank with that delivered by PF delivered via portable oxygen concentrator. Hypotheses were (1) a lung model of COPD with non-zero end-expiratory flow decreases F IO 2 for CF more than for PF, and (2) CF and PF perform differently in terms of F IO 2 delivery, despite having equivalent settings. METHODS: Normal and COPD lung models were simulated (IngMar Medical ASL 5000) using published human data: normal: breathing frequency ‫؍‬ 15 breaths/min, R in ‫؍‬ 4 cm

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Section: Discussionmentioning

confidence: 99%

Effect of the Anatomic Reservoir on Low-Flow Oxygen Delivery Via Nasal Cannula: Constant Flow Versus Pulse Flow With Portable Oxygen Concentrator

Zhou

Chatburn

2014

Respir Care

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“…Previous studies have evaluated oxygen-conserving device performance in ILD, 17,26,27 but the small number of subjects (Ͻ 10) in those studies makes it difficult to extract universally applicable conclusions. In contrast to our findings, studies assessing various DOD systems 26,27 have reported performance equivalent to the continuous flow types. However, those devices were tested at a low level of exercise, so their efficacy was not examined under technical or physiological stress.…”

Section: Discussionmentioning

confidence: 99%

Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

Martí

Pajares²,

Morante³

et al. 2013

Respir Care

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BACKGROUND: Correction of exercise hypoxemia in advanced lung diseases is crucial and often challenging. However, oxygen-conserving devices have been introduced in the market with limited evidence of effectiveness. In the present study the efficacy of 2 oxygen-conserving devices, a pulse demand oxygen delivery (DOD) system and pendant reservoir cannula (PRC), were evaluated in subjects with COPD and interstitial lung disease (ILD). METHODS: A cross-sectional, crossover study included 28 COPD and 31 ILD subjects with oxygen desaturation on the 6-min walk test (average S pO 2 < 88%). Each subject underwent 3 walk tests with DOD, PRC, and continuous oxygen flow by standard nasal cannula (CFNC), in random order, taking average S pO 2 > 90% as the resaturation criterion. RESULTS: Exercise desaturation was corrected in 79%, 79%, and 86% of COPD subjects with CFNC, DOD, and PRC, respectively, and in 77%, 61%, and 81% of ILD subjects with CFNC, DOD, and PRC, respectively. When compared to CFNC, the oxygen-conserving devices showed similar efficacy, except a lower performance for the DOD in the ILD subjects (P ‫؍‬ .01). CONCLUSIONS: Although these oxygen-conserving devices corrected exercise hypoxemia in most COPD and ILD subjects, correction was not achieved in about 20% of the severe COPD subjects, regardless of the device, and in nearly 40% of the ILD subjects with the DOD device. These findings underscore that individualized adjustment of oxygen flow is needed for optimal correction of exercise hypoxemia, especially with a DOD in an ILD patient. (Clinical Trials.gov NCT01086891).

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“…Demand oxygen delivery devices have been shown to extend the supply of gaseous cylinder and liquid oxygen by up to seven times that of the continuous flow system.' 6 The ability of the DODS to extend the oxygen supply beyond that of a continuous flow cylinder is not in doubt. The comparable oxygenation provided by the two systems in subjects with COPD who severely desaturate during submaximal exercise has not, however, previously been investigated.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the efficacy of a demand oxygen delivery system with continuous low flow oxygen in subjects with stable COPD and severe oxygen desaturation on walking.

Roberts

Bell

Wedzicha

1996

Thorax

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Background -Provision of ambulatory oxygen using an intermittent pulsed flow regulated by a demand oxygen delivery system (DODS) greatly increases the limited supply time of standard portable gaseous cylinders. The efficacy of such a system has not previously been studied during submaximal exercise in subjects with severe chronic obstructive pulmonary disease (COPD) in whom desaturation is likely to be great and where usage is often most appropriate.

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Demand Oxygen Delivery for Patients with Restrictive Lung Disease

Cited by 17 publications

References 11 publications

Effect of the Anatomic Reservoir on Low-Flow Oxygen Delivery Via Nasal Cannula: Constant Flow Versus Pulse Flow With Portable Oxygen Concentrator

Effect of the Anatomic Reservoir on Low-Flow Oxygen Delivery Via Nasal Cannula: Constant Flow Versus Pulse Flow With Portable Oxygen Concentrator

Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

Comparison of the efficacy of a demand oxygen delivery system with continuous low flow oxygen in subjects with stable COPD and severe oxygen desaturation on walking.

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