Delusional Disorders--Are They Simply Paranoid Schizophrenia?

Marneros, Andreas; Pillmann, Frank; Wustmann, Tobias

doi:10.1093/schbul/sbq125

Cited by 57 publications

(88 citation statements)

References 33 publications

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“…There are also plausible neurobiological accounts consistent with the cognitive account (Fletcher and Frith, 2009; Whitford et al, 2012). …”

Section: The Traditional Comparator Account Of Misattributed Inner Spmentioning

confidence: 97%

“…The comparator account of inner speech holds that similar motor control processes will underpin the production of sentences in natural language whether they are “spoken” internally or externally. On this basis, several theorists have provided detailed accounts of a comparator account for misattributed inner speech (Seal et al, 2004; Jones and Fernyhough, 2007; Langland-Hassan, 2008; Whitford et al, 2012). Jones and Fernyhough (2007) provide the clearest and most comprehensive explication of such an approach.…”

Section: The Traditional Comparator Account Of Misattributed Inner Spmentioning

confidence: 99%

“…The basic plausibility of extending the comparator account beyond bodily actions to explain misattributed inner speech is ubiquitously accepted both within the expanding literature on the sense of agency (e.g., Vosgerau and Newen, 2007; Synofzik et al, 2008a) and beyond (e.g., Carruthers, 2011; Whitford et al, 2012). Authors regularly appeal to the account as a plausible explanation for results from behavioral studies (e.g., Li et al, 2002; Johns et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

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A new comparator account of auditory verbal hallucinations: how motor prediction can plausibly contribute to the sense of agency for inner speech

Swiney¹,

Sousa²

2014

Front. Hum. Neurosci.

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The comparator account holds that processes of motor prediction contribute to the sense of agency by attenuating incoming sensory information and that disruptions to this process contribute to misattributions of agency in schizophrenia. Over the last 25 years this simple and powerful model has gained widespread support not only as it relates to bodily actions but also as an account of misattributions of agency for inner speech, potentially explaining the etiology of auditory verbal hallucination (AVH). In this paper we provide a detailed analysis of the traditional comparator account for inner speech, pointing out serious problems with the specification of inner speech on which it is based and highlighting inconsistencies in the interpretation of the electrophysiological evidence commonly cited in its favor. In light of these analyses we propose a new comparator account of misattributed inner speech. The new account follows leading models of motor imagery in proposing that inner speech is not attenuated by motor prediction, but rather derived directly from it. We describe how failures of motor prediction would therefore directly affect the phenomenology of inner speech and trigger a mismatch in the comparison between motor prediction and motor intention, contributing to abnormal feelings of agency. We argue that the new account fits with the emerging phenomenological evidence that AVHs are both distinct from ordinary inner speech and heterogeneous. Finally, we explore the possibility that the new comparator account may extend to explain disruptions across a range of imagistic modalities, and outline avenues for future research.

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“…There are also plausible neurobiological accounts consistent with the cognitive account (Fletcher and Frith, 2009; Whitford et al, 2012). …”

Section: The Traditional Comparator Account Of Misattributed Inner Spmentioning

confidence: 97%

Section: The Traditional Comparator Account Of Misattributed Inner Spmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A new comparator account of auditory verbal hallucinations: how motor prediction can plausibly contribute to the sense of agency for inner speech

Swiney¹,

Sousa²

2014

Front. Hum. Neurosci.

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“…Lebensjahr entwickelt ist jedoch vom Konzept her ein Prozess der neuronalen Entwicklungsstörung [8]. Aus unserer Diagnosegruppe F22 könnte man einige der Gruppe VLOSLP zuordnen [2,3,11].…”

Section: Diagnostikunclassified

Diagnostik und medikamentöse Therapie bei schizophrenen Patienten im Alter

Jagsch¹,

Dietmaier

Jagsch

et al. 2016

Neuropsychiatr

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The referral diagnoses of patients suffering from many years of schizophrenic type illnesses were largely in compliance with the diagnostic criteria, a much more difficult issue for the referring doctors was the allocation of patients with a first occurrence of delusional symptoms. Those patients who were allocated to the diagnostic group schizophrenia differed significantly from patients from the group with delusional disorders.

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“…Several studies have reported the frequency of nonprominent hallucinations in DD to be around 18.6-45.3% (De Portugal et al, 2009;Marneros et al, 2012;González-Rodríguez et al, 2013). However, there is little evidence supporting the efficacy of antipsychotic treatment for nonprominent hallucinations in these patients.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of long-acting injectable antipsychotics in delusional disorders with nonprominent hallucinations and without hallucinations

González-Rodríguez

Molina-Andreu²,

Penadés³

et al. 2014

International Clinical Psychopharmacology

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The presence of nonprominent hallucinations in delusional disorder (DD) has been accepted by the current Diagnostic and Statistical Manual of Mental Disorders, 5th ed. A recent meta-analysis revealed that patients with schizophrenia treated with long-acting atypical antipsychotics showed a significant improvement in psychotic symptoms. However, little research has been conducted on DD. Our goal was to investigate demographic and clinical differences between two subgroups of DD patients, those with nonprominent hallucinations and those without hallucinations, and to determine treatment effectiveness of long-acting antipsychotics in these patients. We conducted a longitudinal observational study with a 6-month follow-up period in a clinical group of 45 DD outpatients. Positive and Negative Syndrome Scale (PANSS), Personal and Social Performance Scale, and Hamilton Rating Scale for Depression-17 (HRSD-17) were used for assessment. Age at onset of DD, scores in baseline assessment scales, and drug compliance were included in the analysis as potential confounders. When uncorrected for influencing factors, patients treated with long-acting antipsychotics showed lower scores in PANSS positive and negative subscales. There were no statistically significant clinical subgroup×treatment group interactions for any of the scores in assessment scales at 6 months. After adjustment, patients treated with long-acting antipsychotics showed lower scores in the PANSS negative subscale and a tendency toward improvement in scores in the PANSS positive subscale. Our study suggests that risperidone long-acting injection and paliperidone palmitate long-acting injection may be useful in the treatment of DD patients, specifically those with nonprominent hallucinations.

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Delusional Disorders--Are They Simply Paranoid Schizophrenia?

Abstract: The findings of this study support the assumption that DDs are a separate entity and only exceptionally can be a prodrome of schizophrenia.

Cited by 57 publications

References 33 publications

A new comparator account of auditory verbal hallucinations: how motor prediction can plausibly contribute to the sense of agency for inner speech

A new comparator account of auditory verbal hallucinations: how motor prediction can plausibly contribute to the sense of agency for inner speech

Diagnostik und medikamentöse Therapie bei schizophrenen Patienten im Alter

Effectiveness of long-acting injectable antipsychotics in delusional disorders with nonprominent hallucinations and without hallucinations

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