Delivery before 32 weeks of gestation for maternal pre-eclampsia: neonatal outcome and 2-year developmental outcome

Excess Soluble fms-Like Tyrosine Kinase 1 and Low Platelet Counts in Premature Neonates of Preeclamptic Mothers

“…[1][2][3][4][5][6][7] This study confirmed previous findings of a greater incidence of SGA but lower platelet counts in preterm infants with maternal preeclampsia. To the best of our knowledge, this is the first study to demonstrate that infants with maternal preeclampsia had higher cord blood sFlt-1 but lower PlGF and VEGF levels.…”

“…[1][2][3][4][5][6] Neonatal thrombocytopenia is observed in 26% to 47% of infants who are delivered to mothers with preeclampsia complicated with hemolysis, elevated liver enzymes, and low platelets syndrome. [7][8][9][10][11] This abnormality affects the long-term outcome when extreme prematurity or intrapartum asphyxia is coexistent.…”

Prediction of Neurodevelopmental and Sensory Outcome at 5 Years in Norwegian Children Born Extremely Preterm

“…The effect of preeclampsia on cognitive function in children born extremely preterm, being SGA or of appropriate weight, has not been extensively studied, and available results are conflicting. 49,50 The proportion of children with minor visual defects and blindness was similar to previous studies 20,24,28,51 and much higher than reported for term children. 17,51,52 The negative effect of significant ROP on later visual function confirms earlier studies, 52 whereas the impact of mild ROP is more unclear.…”

Transient Hypothyroxinemia in Severe Hypertensive Disorders of Pregnancy

“…It could well be an independent cause of impaired brain development and the observed impairment of neuropsychological development in infants who were born growth restricted. 37,38 These data stress the importance of an adequate follow-up of growth-restricted preterm infants, because they are at risk of hypothyroxinemia, and follow-up of preterm neonates shows a high prevalence of developmental disorders, especially after low postnatal thyroid hormone levels. 39 In summary, we have demonstrated that transient hypothyroxinemia is common in women with severe hypertensive disorders, but it is not associated with an increased incidence of thyroid disorders.…”