Delayed onset of Takotsubo syndrome after epileptic seizure

Immediate versus delayed detection of Takotsubo syndrome after epileptic seizures

“…In 23 cases, TTS was reported to develop immediately after the seizure and signs of TTS were already present at hospital admission (Table 1) [4][5][6]8,9,13,14,16,[20][21][22][23][24][25][26][27][28][29][30][31][32][33][34]. In the remaining 25 cases, detection of TTS was reported 5-288 (mean 50) hours after the seizure (Table 2) [3,[10][11][12][17][18][19][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49].…”

“…The prevalence of negative T-waves was higher among patients with delayed than with immediate detection of TTS (Table 3). In 7 of the 25 cases with delayed detection of TTS, an earlier ECG performed at admission was reported which showed no ST-or T-wave abnormalities [10,12,19,36,45,48,49].…”

Modeling Takotsubo syndrome with patient-specific induced pluripotent stem cell-derived cardiomyocytes

“…Another approach would be the exploration of TTSassociated biomarkers, which has already started by the identification of certain miRNAs (Jaguszewski et al, 2014) to specifically differentiate TTS from a STEMI. While the model generated in this thesis focuses on rather short timescales, some TTS patients seem to show a longer timeframe to develop symptoms (Ghose and Banerjee, 2019;Stöllberger and Finsterer, 2019). These observations suggest a cumulative toxic effect of catecholamine.…”