Delayed MR imaging of the liver: correlation of delayed enhancement of hepatic tumors and pathologic appearance

Abstract

Ultradelayed MR imaging can characterize different tissue components within various hepatic tumors.

Differentiating Focal Eosinophilic Infiltration from Metastasis in the Liver with Gadoxetic Acid-Enhanced Magnetic Resonance Imaging

“…Non-spherical shape (76-85%), ill-defined margin (79-90%), isointensity on T1 weighted images (55-79%), hyperintensity on T2-weighted images (77-94%), and variable enhancement on dynamic imaging may be suggestive of FEIs (6, 8-10, 12, 16), which is consistent with our findings. In contrast, the majority of hepatic metastases in our study showed well-defined margin, spherical shape, hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and rim enhancement on dynamic images as reported previously (20,(24)(25)(26)(27).…”

“…Several investigators (20,(24)(25)(26)(27) reported that the MRI features of hepatic metastasis commonly include hypointensity on T1 and hyperintensity on T2-weighted images, and these findings are attributable to a lack of glycogen within tumor cells and a relative increase in the amount of water in extracellular spaces or tumoral matrices (20). In our study, isointensity on T1-weighted images in FEIs was an important distinguishing finding that was different from hepatic metastasis.…”

Intrahepatic peripheral cholangiocarcinoma in cirrhosis patients may display a vascular pattern similar to hepatocellular carcinoma on contrast-enhanced ultrasound

“…Of course, this will not occur with US contrast agents that are pure intravascular tracers. [27][28][29][30][31][32] The results of this study raise major concerns about the use of CEUS as the only dynamic imaging technique for noninvasive diagnosis. To our knowledge, the only study that has prospectively evaluated the diagnostic accuracy of CEUS for HCC diagnosis showed that CEUS misclassified a 16-mm ICC as HCC.…”

MR imaging of the liver with Gd-BOPTA: Quantitative analysis of T1-weighted images at two different doses

“…However, regardless of cell type, solid liver lesions show a wide range of enhancement after Gd-BOPTA because the extracellular component of the contrast agent produces non-specific tissue enhancement, resulting in heterogenous enhancement of malignant liver tumors. For example, metastases show persistent central enhancement with peripheral wash-out (10,11). This enhancement characteristics has also been reported to occur with exclusively extra-cellular gadolinium-based contrast agents and has been found to be unique to malignant lesions.…”