Delayed Development of Tuberculous Bronchoesophageal Fistulas in a Patient With AIDS Necessitates Endoscopic Surgery

Dronda, Fernando; Fernández-Martín, Ignacio; González-López, A.; Puente, Luis

doi:10.1093/clinids/21.4.1062

Cited by 9 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our case, as in other studies [14], chemotherapy with a regimen of 3 drugs (rifampicin, isoniazid and pyrazinamide) was started and was initially successful, but subsequently required complementary esaphogoscopy with a therapeutic intervention to alleviate the persistence of a minor symptom (paroxysmal cough when swallowing liquids), which is probably associated with the size of the fistula’s orifice.…”

Section: Discussionsupporting

confidence: 67%

Bronchoesophageal Fistulae Secondary to Tuberculosis

Lado¹,

Gómez

Barrón³

et al. 2002

Respiration

View full text Add to dashboard Cite

An elderly patient with a bronchoesophageal fistula secondary to tuberculosis and a 3-month history of cough and dysphagia worsening with deglutition was admitted to hospital. Radiological examination and CT of the thorax revealed mediastinal adenopathy. Bronchoscopy, esophagoscopy and esophagraphy confirmed the presence of a bronchoesophageal fistula. Histological examination of the esophagus and bronchial biopsy specimens revealed nonnecrotic granulomas, and the acid-fast bacilli tested positive for Mycobacterium tuberculosis in respiratory secretions. Antituberculous treatment was started after diagnosis of intrathoracic lymph node tuberculosis with bronchoesophageal fistulization. A month and a half after initiating treatment, paroxistic coughing during deglutition persisted. An esophagoscopy was performed, and the orifice was closed with a fibrin tissue. After 9 months of treatment, the patient was asymptomatic and in good health.

show abstract

Section: Discussionsupporting

confidence: 67%

Bronchoesophageal Fistulae Secondary to Tuberculosis

Lado¹,

Gómez

Barrón³

et al. 2002

Respiration

View full text Add to dashboard Cite

show abstract

“…In the other case described in the literature [ 3 ], no clinical improvements were identified until CMV infection was identified and treated, which necessitates the skilled diagnosis of coinfections. Table 2 compares clinical and epidemiological aspects between tuberculosis and CMV infection in the gastrointestinal tract, demonstrating their main differences [ 9 , 16 , 26 , 27 ]. The lesions' appearances, found in our case's colonoscopy, were suggestive of ulcerative-type intestinal tuberculosis, but the significant ulceration extension that was found led to the suspicion of a coinfection responsible for magnifying the damage to the epithelium.…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal CMV Disease and Tuberculosis in an AIDS Patient: Synergistic Interaction between Opportunistic Coinfections

Fernandes

Cardoso

Altoé

et al. 2018

Case Reports in Medicine

View full text Add to dashboard Cite

The AIDS pandemic has made diseases such as tuberculosis, CMV disease, and other opportunistic infections more prevalent; these diseases may even be found to be associated among themselves, and the natural history of each disease may present in an unusual manner. We report the case of a 41-year-old man with HIV (CD4 of 144 cells/dL) and HCV with hematochezia due to tuberculosis in the ileocecal valve and descending colon and CMV tissue invasive disease in the esophagus and descending colon. Coinfection among tuberculosis and cytomegalovirus in the gastrointestinal tract was described only once in a patient with a recent diagnosis of HIV that affected the distal ileum and ascending colon. We will discuss the peculiarities of the case and the behavior of the immune system in the face of simultaneous opportunistic infections. This is a challenging scenario that has scarce publications and is of great clinical importance.

show abstract

“…[6][7][8] To our knowledge, although oesophagobronchial fistulas are a complication of mediastinal lymph node tuberculosis and of HSV oesophageal ulceration, this is the first case of a VZV oesophageal ulcer causing fistulisation in a patient with AIDS. [9][10][11][12][13] "Recognition of the spectrum of the clinical manifestation of zoster in the HIV infected host is of increasing importance in light of the changing natural history of HIV infection in the era of improved therapeutic and prophylactic regimens"…”

Section: Discussionmentioning

confidence: 99%