Degradation of halogenated aromatic compounds

Commandeur, L.C.M.; Parsons, John R.

doi:10.1007/978-94-011-3452-1_10

Cited by 15 publications

(20 citation statements)

References 140 publications

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“…From the above results, most of our isolates appeared to degrade 4‐CBA through 4‐hydroxybenzoate, while one isolate, HR20, mineralized 4‐CBA via formation of 4‐chlorocatechol. While the two degradative pathways are described among other isolates of the previous works [6,13,22,23], the majority of organisms able to grow on 4‐CBA appear to mineralize it through 4‐hydroxybenzoate, which is consistent with the suggestion that dehalogenation by hydroxylation is very specific for the para position of halobenzoates in the microbial metabolism of halogenated benzoic acid [24]. It is interesting that the 3‐chlorobenzoate‐utilizing organisms degrade 3‐chlorobenzoate mainly via chlorocatechol [25,26], while our 4‐CBA‐degrading isolates mineralize 4‐CBA mainly via the corresponding hydroxybenzoate.…”

Section: Resultssupporting

confidence: 83%

Phylogenetic and phenotypic diversity of 4-chlorobenzoate-degrading bacteria isolated from soils

Min

Kim

et al. 2000

FEMS Microbiology Ecology

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Twenty numerically dominant 4-chlorobenzoate (4-CBA)-degrading bacteria were isolated from agricultural soils. The isolates were able to utilize 4-CBA as a sole source of carbon and energy. A total of 65% of the isolates was identified to the species level by fatty acid methyl ester (FAME) analysis, and the isolates were strains of Micrococcus, Pseudomonas, Oerskovia, Cellulomonas, and Arthrobacter species. The chromosomal DNA patterns of the isolates obtained by polymerase chain reaction (PCR) amplification of repetitive extragenic palindromic (REP) sequences were distinct from each other. Most of the isolates grew rapidly in 4-CBA medium, but their substrate utilization capabilities were generally restricted. Plasmid DNAs were detected from 55% of the isolates, and one strain, HR7, was shown to have self-transmissible, 4-CBA degradative plasmids. 4-CBA degradative enzymes were inducible by the presence of 4-CBA and most of the isolates appeared to mineralize it through 4-hydroxybenzoate rather than 4-chlorocatechol.

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Section: Resultssupporting

confidence: 83%

Phylogenetic and phenotypic diversity of 4-chlorobenzoate-degrading bacteria isolated from soils

Min

Kim

et al. 2000

FEMS Microbiology Ecology

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“…Nevertheless, genes for some of these enzymes are evolutionary related to each other. One illustrative example is a group of multicomponent dioxygenases involved in the NADH-dependent incorporation of central metabolic route for the degradation of cl chols, which arise in the conversion of chlorin chlorinated benzoates, 2,4-dichlorophenoxyacetic rophenol (30,35,181). A variety of peripheral enzy formation of chlorocatechols (step 1).…”

Section: Genes For Peripheral Enzymesmentioning

confidence: 99%

Molecular mechanisms of genetic adaptation to xenobiotic compounds.

Meer

Vos

Harayama

et al. 1992

Microbiological Reviews

388

157

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“…However, no isolations or O 2 kinetic studies were reported. With respect to 3CBA degradation, hydroxylations catalyzed by hydrolases or monooxygenases, or initial reduction of 3CBA, may be alternative mechanisms which do not require low-O 2 -affinity dioxygenases in the initial metabolic steps (5,11,21). In 1972 Johnston et al reported the degradation of 3CBA by a Pseudomonas sp., in which they detected as intermediates some phenolic compounds which resembled 3-hydroxybenzoate and gentisate (24).…”

mentioning

confidence: 99%

Isolation of Alcaligenes sp. strain L6 at low oxygen concentrations and degradation of 3-chlorobenzoate via a pathway not involving (chloro)catechols

Krooneman

Wieringa

Moore

et al. 1996

Appl Environ Microbiol

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Isolations of 3-chlorobenzoate (3CBA)-degrading aerobic bacteria under reduced O 2 partial pressures yielded organisms which metabolized 3CBA via the gentisate or the protocatechuate pathway rather than via the catechol route. The 3CBA metabolism of one of these isolates, L6, which was identified as an Alcaligenes species, was studied in more detail. Resting-cell suspensions of L6 pregrown on 3CBA oxidized all known aromatic intermediates of both the gentisate and the protocatechuate pathways. Neither growth on nor respiration of catechol could be detected. Chloride production from 3CBA by L6 was strictly oxygen dependent. Cell-free extracts of 3CBA-grown L6 cells exhibited no catechol dioxygenase activity but possessed protocatechuate 3,4-dioxygenase, gentisate dioxygenase, and maleylpyruvate isomerase activities instead. In continuous culture with 3CBA as the sole growth substrate, strain L6 demonstrated an increased oxygen affinity with decreasing steady-state oxygen concentrations.

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Degradation of halogenated aromatic compounds

Cited by 15 publications

References 140 publications

Phylogenetic and phenotypic diversity of 4-chlorobenzoate-degrading bacteria isolated from soils

Phylogenetic and phenotypic diversity of 4-chlorobenzoate-degrading bacteria isolated from soils

Molecular mechanisms of genetic adaptation to xenobiotic compounds.

Isolation of Alcaligenes sp. strain L6 at low oxygen concentrations and degradation of 3-chlorobenzoate via a pathway not involving (chloro)catechols

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