2012
DOI: 10.1902/jop.2012.110627
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Definitive and Differential Diagnosis of Desquamative Gingivitis Through Direct Immunofluorescence Studies

Abstract: This study has the largest cohort of patients with DG suspected of VBD reported in the literature. The patients were predominantly females who had most often been seen by a periodontist. The definitive diagnosis of DG was most accurately achieved when H & E along with two biopsies for direct IF studies were submitted for testing. H & E studies were particularly important for definitive diagnosis of negative cases. Oral lichen planus was the most common disease presenting as DG, which is consistent with recent … Show more

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Cited by 50 publications
(40 citation statements)
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“…[101112] Therefore, gingival disorders as silent epidemic[7] are most commonly chronic bacterial infection that affects on 60–90% of school children and nearly 100% of adults. [3940] Furthermore, hospitalization has negative effects on oral health conditions of hospitalized patients and accelerates the accumulation of dental plaque that is associated with the destruction of mucosal membranes and increases the rate of gingivitis. [41] In addition, because the oral cares of hospitalized patients are not the right priority of nurses,[41] However, in these patients, oral problems are rapidly intensified and increased the nosocomial infections.…”
Section: Discussionmentioning
confidence: 99%
“…[101112] Therefore, gingival disorders as silent epidemic[7] are most commonly chronic bacterial infection that affects on 60–90% of school children and nearly 100% of adults. [3940] Furthermore, hospitalization has negative effects on oral health conditions of hospitalized patients and accelerates the accumulation of dental plaque that is associated with the destruction of mucosal membranes and increases the rate of gingivitis. [41] In addition, because the oral cares of hospitalized patients are not the right priority of nurses,[41] However, in these patients, oral problems are rapidly intensified and increased the nosocomial infections.…”
Section: Discussionmentioning
confidence: 99%
“…Inflammatory serum markers such as CRP are elevated in AgP compared to ChP [31][32][33][34][35][36].…”
Section: Classification Of Periodontal Diseasesmentioning
confidence: 96%
“…The biopsy for routine histology and DIF should be taken from the vesicle, edge of an ulcer, or erythema and tissue. Histopathology discloses sub-epithelial clefting with preservation of variable inflammation (7). In the DIF technique, MMP patient's biopsy specimens illustrate positive DIF studies for IgG, C3, and often IgA in 50% to 80% of cases.…”
Section: Introductionmentioning
confidence: 99%