Defining arthritis and measuring functional status in elders: methodological issues in the study of disease and physical disability.

Guccione, Andrew A.; Felson, David T.; Anderson, Jennifer J.

doi:10.2105/ajph.80.8.945

Cited by 163 publications

(92 citation statements)

References 14 publications

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“…The musculoskeletal conditions sarcopenia and OA have both been linked with increased risk of disability (21,22) and falls (10,11) in the aging population. The results from the present study indicate that pain may contribute further to disability and falls risk in women by exacerbating agerelated muscle strength and quality declines.…”

Section: Discussionmentioning

confidence: 99%

Prospective study of self‐reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community‐dwelling older adults

Scott¹,

Blizzard²,

Fell³

et al. 2011

Arthritis Care & Research

109

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Objective. To examine the potential role of self-reported joint pain, stiffness, and dysfunction, and radiographic osteoarthritis (ROA), in sarcopenia progression and falls risk in older adults. Methods. Seven hundred nine older adults (50% women, mean ؎ SD age 62 ؎ 7 years) were examined at baseline and followup (mean ؎ SD 2.6 ؎ 0.4 years). ROA was assessed using the Altman atlas, and pain at 7 anatomic sites was self-reported. Dual x-ray absorptiometry assessed leg lean mass, dynamometry assessed knee extension and whole leg strength, leg muscle quality (LMQ) was calculated as whole leg strength relative to leg lean mass, and the Physiological Profile Assessment assessed falls risk. Results. In women only, baseline knee pain predicted a greater decline in knee extension strength, whole leg strength, and LMQ, and a greater increase in falls risk. Severe knee pain, stiffness, and dysfunction predicted greater declines in knee extension strength and increases in falls risk (all P < 0.05). Hip pain also predicted a greater decline in knee extension strength (؊1.53 kg; 95% confidence interval [95% CI] ؊2.95, ؊0.11). No associations were observed between pain and sarcopenia indicators in men. Somewhat surprisingly, higher baseline total knee ROA score predicted a greater increase in mean leg lean mass (0.05 kg; 95% CI 0.02, 0.08) in both sexes. A path analysis demonstrated that knee ROA may contribute to declines in LMQ in women, through increases in pain, stiffness, and dysfunction. Conclusion. Knee and hip pain may directly contribute to the progression of sarcopenia and increased falls risk in older women.

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Section: Discussionmentioning

confidence: 99%

Prospective study of self‐reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community‐dwelling older adults

Scott¹,

Blizzard²,

Fell³

et al. 2011

Arthritis Care & Research

109

View full text Add to dashboard Cite

show abstract

“…Kyphosis could also have a negative effect on visual exploration of the environment during street crossing because of the associated impairment of cervical mobility (Quek et al, 2013). Similarly, osteoarthritis, a common inflammatory joint disorder in older people, is associated with difficulty walking and climbing stairs, as well as a higher risk of falling (Guccione et al, 1990;Hanlon et al, 2002;Hochberg et al, 1995).…”

Section: Impact Of Physical Changesmentioning

confidence: 99%

Review of safety and mobility issues among older pedestrians

Tournier

Dommès²,

Cavallo³

2016

Accident Analysis & Prevention

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a b s t r a c tAlthough old people make up an extremely vulnerable road-user group, older pedestrians' difficulties have been studied less extensively than those of older drivers, and more knowledge of this issue is still required. The present paper reviews current knowledge of older-adult problems with the main components of pedestrian activity, i.e., walking and obstacle negotiation, wayfinding, and road crossing. Compared to younger ones, old pedestrians exhibit declining walking skills, with a walking speed decrease, less stable balance, less efficient wayfinding strategies, and a greater number of unsafe road crossing behaviors. These difficulties are linked to age-related changes in sensorial, cognitive, physical, and self-perception abilities. It is now known that visual impairment, physical frailty, and attention deficits have a major negative impact on older pedestrians' safety and mobility, whereas the roles of self-evaluation and self-regulation are still poorly understood. All these elements must be taken into consideration, not only in developing effective safety interventions targeting older pedestrians, but also in designing roads and cars. Recent initiatives are presented here and some recommendations are proposed.

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“…The disease frequently leads to disability, especially in elderly patients (1,2). Little is known, however, about the course of disability over time in patients with OA.…”

Section: Introductionmentioning

confidence: 99%

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

Dijk

Dekker

Veenhof

et al. 2006

Arthritis & Rheumatism

215

148

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Objective. To systematically review studies describing the course of functioning in patients with osteoarthritis (OA) of the hip or knee and identifying potential prognostic factors. Methods. A systematic search was performed. Studies involving patients with hip or knee OA, >6 months of followup, and outcome measures on functional status or pain were included. Methodologic quality was assessed using a standardized set of 11 criteria; a qualitative data analysis was performed.Results. Approximately 6,500 titles and abstracts were screened and 48 publications were considered for inclusion. Eighteen studies, 4 of which met the high methodologic quality criteria, were included. For hip OA, there was limited evidence that functional status and pain do not change during the first 3 years of followup. After 3 years, however, a worsening of functional status and pain was seen. For knee OA, there was conflicting evidence for the first 3 years and limited evidence for worsening of pain and functional status after 3 years. Furthermore, limited evidence was established for negative associations between future functional status and laxity, proprioceptive inaccuracy, age, body mass index, and knee pain intensity. In contrast, greater muscle strength, better mental health, better self-efficacy, social support, and more aerobic exercise were protective factors in the first 3 years. Conclusion. Pain and functional status in hip or knee OA seem to deteriorate slowly, with limited evidence for worsening after 3 years of followup. In specific subgroups, prognosis in the first 3 years of followup was either worse or better, as both risk factors and protective factors were identified. Prognostic factors included biomechanical factors, psychological factors, clinical factors, and treatment modalities. To strengthen the evidence, further high-quality longitudinal research on hip or knee OA functioning is needed.

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Defining arthritis and measuring functional status in elders: methodological issues in the study of disease and physical disability.

Cited by 163 publications

References 14 publications

Prospective study of self‐reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community‐dwelling older adults

Prospective study of self‐reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community‐dwelling older adults

Review of safety and mobility issues among older pedestrians

Course of functional status and pain in osteoarthritis of the hip or knee: A systematic review of the literature

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