Deficient brightness discrimination acquisition produced by daily intracranial injections of penicillin in rats

Woodruff, Michael L.; Kearley, Richard C.; Isaacson, Robert L.

doi:10.1016/s0091-6773(74)92251-2

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General Discussion and Conclusion1

Penicillin1

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1975

1985

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Cited by 4 publications

(2 citation statements)

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“…The large number of observations on hippocampal function suggest that the system must be intact in order to adjust behavior to new requirements under circumstances of environmental uncertainty. In other words, the hippocampal function by suppressing the older memories allows new actions to be taken, new memories to be formed (Isaacson, 1974(Isaacson, , 1975. Two important issues should, however, be suggested.…”

Section: General Discussion and Conclusionmentioning

confidence: 99%

“…Penicillin did not produce any effect on the acquisition of position discrimination cnmmation reinforced with food. Woodruff et al (1974) found that daily injection of penicillin into the hippocampus retarded the acquisition of a brightness discrimination in a two-bar Skinner box. The results likely indicate an interference with the visual system, because the drug injected into the overlying neocortex produced more retardation.…”

Section: Penicillinmentioning

confidence: 98%

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