Deer antler base as a traditional Chinese medicine: A review of its traditional uses, chemistry and pharmacology

Wu, Feifei; Li, Huaqiang; Jin, Lei; Li, Xiaoyü; Ma, Yongsheng; You, Jhih-Shih; Li, Shuying; Xu, Yongping

doi:10.1016/j.jep.2012.12.008

Cited by 141 publications

(98 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The AV has elicited scientific interest as a promise for several health treatments [11,13,18,32]. For example, AV is a potential therapeutic agent for managing osteoporosis in rats [24,25], or is capable of inducing and guiding neurite outgrowth of rat sensory neurons in vitro [20].…”

Section: Introductionmentioning

confidence: 99%

Antler velvet is thicker in adult than in yearling pampas deer (Ozotoceros bezoarticus): a histological study

et al. 2017

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Antler velvet is thicker in adult than in yearling pampas deer (Ozotoceros bezoarticus): a histological study

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Pilose antler, the young unossified antler of the sika and red deer, is a rare animalsourced traditional Chinese medicine (Wu et al, 2013). This medicine contains a variety of ingredients, such as hormones (Quan, Zhang, & Chang, 2014), polysaccharides, polypeptides (Zhang et al, 2012), cytokines (Lin, Deng, Wu, Chen, & Li, 2011) and vitamins (Wu et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…This medicine contains a variety of ingredients, such as hormones (Quan, Zhang, & Chang, 2014), polysaccharides, polypeptides (Zhang et al, 2012), cytokines (Lin, Deng, Wu, Chen, & Li, 2011) and vitamins (Wu et al, 2013). Pilose antler complex crude extract is widely used as a healthcare product in China and South Korea (Lee et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Pilose antler complex crude extract is widely used as a healthcare product in China and South Korea (Lee et al, 2015). In addition to diminishing the inflammatory effects of pathogens (Lin et al, 2011;Quan et al, 2014;Wu et al, 2013) and enhancing the immune effects of the body (Zha et al, 2013), pilose antler has been demonstrated to be involved in the control of tumour growth (Nonaka et al, 2008;Tang et al, 2015;Zha et al, 2016). Investigations have shown that the inhibitory effects of pilose antler on inflammation and tumour growth are related to changes in the immune system induced by pilose antler (Nonaka et al, 2008;Zha et al, 2016;Zhang, Li, Qu, Luo, & Drummen, 2016).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Distinctive effects of pilose antler on mouse peripheral blood immune cell populations

Zheng

Fan

et al. 2017

Food and Agricultural Immunology

View full text Add to dashboard Cite

Pilose antler is a rare animal-sourced traditional Chinese medicine that has been demonstrated to cause a change in total immunity. Little is known about its specific effect on immune cells. In this study, the immunological modulatory effects of pilose antler extract on mice were investigated. Mice were gavaged daily for 7 days with pilose antler extracts, and peripheral blood was analysed by flow cytometry. Our results show that pilose antler extract exerted distinctive effects on the different immune cell types analysed. Pilose antler gavage transiently increased T cell percentage and decreased B cell percentage in peripheral blood. After treatment, the proliferation of killer and helper T cells was stimulated in the short term, but in the longer term, NK and memory T cell populations were increased. These results suggest that pilose antler treatment has both transient and long-term effects on the immune system in mice.ARTICLE HISTORY

show abstract

“…TCM (traditional Chinese medicine) is a holistic system of medicine and has been used to treat many diseases for thousands of years in China. The earliest books on traditional Chinese medicine published about in the Han Dynasty, that is Shen Nong Ben Cao Jing [9].…”

mentioning

confidence: 99%

The Potential Targets of Chinese Medicines in the Treatment of Parkinson’s Disease: Old Wine in New Bottles

Zhang¹,

Li²,

Wang³

et al. 2016

JPP

View full text Add to dashboard Cite

This article systematically reviews the present research situation of the pathogenesis of PD (Parkinson's disease) and our recent research over the past decade, to discuss the potential targets of many TCM (traditional Chinese medicines) in prevention and treatment of PD, such as against oxidative stress (Astragaloside, protocatechuic aldehyde, Liu-Wei-Di-Huang), anti-apoptosis (Geniposide, Zhichan powder), improve mitochondrial function (Paeoniflorin, Da-Bu-Yin-Wan), inhibition of protein aggregation (Panax ginseng, Irisflorentin), induce autophagy (piperine, Paeoniflorin), and many other mechanisms and multiple effectiveness (Saponins, Acanthopanax). With the research and development in PD pathogenesis and clarifying the targets of a variety of traditional Chinese medicine, especially its monomeric components, the development of traditional Chinese medicine in prevention and treatment of PD will have very broad application value and prospect.

show abstract

Deer antler base as a traditional Chinese medicine: A review of its traditional uses, chemistry and pharmacology

Cited by 141 publications

References 19 publications

Antler velvet is thicker in adult than in yearling pampas deer (Ozotoceros bezoarticus): a histological study

Antler velvet is thicker in adult than in yearling pampas deer (Ozotoceros bezoarticus): a histological study

Distinctive effects of pilose antler on mouse peripheral blood immune cell populations

The Potential Targets of Chinese Medicines in the Treatment of Parkinson’s Disease: Old Wine in New Bottles

Contact Info

Product

Resources

About