Deep-vein thrombosis after fracture of the pelvis

White, Richard; Goulet, Julien; Bray, Timothy J.; Daschbach, Martha M.; McGahan, John P.; Hartling, R. P.

doi:10.2106/00004623-199072040-00004

Cited by 68 publications

(2 citation statements)

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“…The first reason is that thromboprophylaxis using fondaparinux with a modified 5‐day hospital stay was applied in all patients in both groups [32]. Several reports have demonstrated that long‐duration prophylaxis is not as effective in TKA compared with total hip arthroplasty [2, 32, 38]. Therefore, a shorter, more intense prophylaxis regimen would be more useful in the prevention of DVT following TKA and relatively safer regarding the incidence of bleeding complications.…”

Section: Discussionmentioning

confidence: 99%

Less blood loss under concomitant administration of tranexamic acid and indirect factor Xa inhibitor following total knee arthroplasty: a prospective randomized controlled trial

Lee

Cho

Khurana

et al. 2012

Knee Surg Sports Traumatol Arthrosc

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Section: Discussionmentioning

confidence: 99%

Less blood loss under concomitant administration of tranexamic acid and indirect factor Xa inhibitor following total knee arthroplasty: a prospective randomized controlled trial

Lee

Cho

Khurana

et al. 2012

Knee Surg Sports Traumatol Arthrosc

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“…Diagnostic studies have revealed that LE DVT has an estimated incidence of 10 to 90% in patients with head injuries. [ 34 , 35 ] Most patients (86%) with trauma who underwent RUSS weekly were diagnosed with LE DVT but were clinically asymptomatic; this highlights the silent nature of LE DVT. [ 36 ] Therefore, implementing RUSS can lower the incidence rates of PE and the subsequent morbidity in and mortality of seriously injured patients.…”

Section: Discussionmentioning

confidence: 99%

Ultrasound surveillance for deep venous thrombosis and subsequent venous thromboembolism in adults with trauma: A systematic review and meta-analysis

Al-Sharydah,

Alshahrani,

Maghrabi

et al. 2023

Medicine

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Background: Studies have shown routine ultrasound surveillance (RUSS) will facilitate deep vein thrombosis (DVT) detection in patients with trauma and reduce the subsequent incidence of pulmonary embolism (PE); however, the findings were inconsistent. In adults with trauma at a high risk of venous thromboembolism, this systematic review and meta-analysis compared RUSS outcomes with those of “no RUSS.” Methods: Three databases were screened for relevant articles from inception to October 18, 2021. Randomized controlled trials (RCTs) and observational studies comparing RUSS with no RUSS were included. We used relative risks (RRs), odds ratios (ORs), and mean differences to pool effect estimates for dichotomous and continuous outcomes. The cochrane risk of bias or the risk of bias in non-randomized studies of interventions were used to assess bias risk. The grading of recommendations, assessment, development, and evaluation framework assessed the certainty of the evidence. Findings: Out of 1685 articles, 5 met the inclusion criteria (RCT: 1; observational studies: 4). Observational studies suggested RUSS is associated with higher odds of DVT detection (OR, 4.87; 95% confidence interval [CI], 3.13–7.57; very low certainty). Whereas higher risks of DVT were associated with RUSS in the RCT (distal DVT: RR, 15.48; 95% CI, 7.62–31.48; low certainty, and proximal DVT: RR, 2.37; 95% CI, 1.04–5.39; very low certainty). Reduced odds of PE risk were observed with the RUSS (OR, 0.47; 95% CI, 0.24–0.91; very low certainty). Observational studies indicated that RUSS had an uncertain effect on mortality (OR, 0.46; 95% CI, 0.06–3.49). In the RCT, times to proximal and distal DVT diagnoses were shorter with RUSS (proximal DVT, mean difference 2.25 days shorter [95% CI, 5.74–1.24]; distal DVT, mean differences 1.56 days shorter [95% CI, 4.22–1.12]; very low certainty for both). Increasing bleeding risk was not linked to the RUSS group (RR, 1.24; 95% CI, 0.31–4.92). Interpretation: The RUSS efficacy in adults with trauma at high risk for venous thromboembolism showed that it increases DVT detection, decreases PE incidence, and shortens the time to DVT diagnosis, with an uncertain impact on mortality. The evidence is low or very low in certainty because of bias, inconsistency, imprecision, and indirectness.

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Acetabulum

Lefaivre

Starr

2011

Evidence‐Based Orthopedics

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Deep-vein thrombosis after fracture of the pelvis

Cited by 68 publications

References 0 publications

Less blood loss under concomitant administration of tranexamic acid and indirect factor Xa inhibitor following total knee arthroplasty: a prospective randomized controlled trial

Less blood loss under concomitant administration of tranexamic acid and indirect factor Xa inhibitor following total knee arthroplasty: a prospective randomized controlled trial

Ultrasound surveillance for deep venous thrombosis and subsequent venous thromboembolism in adults with trauma: A systematic review and meta-analysis

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