Deep sedation with propofol for children undergoing ambulatory magnetic resonance imaging of the brain: Experience from a pediatric intensive care unit

Abstract

Propofol can safely facilitate ambulatory magnetic resonance imaging of the brain in children, and it is associated with brief induction, recovery, and discharge times from the hospital. A drop in blood pressure, although mild and transient, does occur. Therefore, appropriate monitoring and preparedness for cardiorespiratory support are essential.

The Effect of the Assignment of a Pre-Sedation Target Level on Procedural Sedation Using Propofol

“…The decrease in systolic blood pressure noted in our study has been previously described for the propofol doses given (9,13). There was no difference in blood pressure changes between the groups noted, which is not surprising because the total dose of propofol given in the two groups was not different.…”

“…Additionally, the patient was placed on a Bispectral Index monitor (BIS). Recent studies BIS to measure awareness during procedural sedation in the ED (7)(8)(9). The EEG analog of BIS has been shown to be more predictive of loss of awareness than the amount of sedative drug given.…”

A Comparison of Dexmedetomidine-Midazolam with Propofol for Maintenance of Anesthesia in Children Undergoing Magnetic Resonance Imaging

“…Recovery after administration of propofol for MRI in children is rapid, complete and associated with few complications. [12][13][14][15] However, there is growing concern regarding the use of propofol infusions in children. First, federal regulatory agencies have expressed concerns regarding the risk of developing propofol infusion syndrome in children.…”

A Presedation Fluid Bolus Does Not Decrease the Incidence of Propofol-Induced Hypotension in Pediatric Patients

“…[5][6][7][8][9][10][11] However, there has been little research to determine whether there is a signifi cant risk to the pediatric patient from propofol-induced hypotension or whether there is an effective method to prevent the induced hypotension, thus prompting this study.…”