2008
DOI: 10.1213/ane.0b013e31818874ee
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A Comparison of Dexmedetomidine-Midazolam with Propofol for Maintenance of Anesthesia in Children Undergoing Magnetic Resonance Imaging

Abstract: Dexmedetomidine-midazolam provides adequate anesthesia for MRI although recovery is prolonged when compared with propofol. Heart rate was slower and systolic blood pressure was greater with dexmedetomidine when compared with propofol. Respiratory indices were similar for the two treatments.

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Cited by 91 publications
(70 citation statements)
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“…Heard et al [11 ] compared a combination of DEX/midazolam with propofol for MRI imaging. Doses employed for DEX were considerably lower (1 mg/kg bolus followed by 0.5 mg/kg/h infusion) than those used by Mason et al (above).…”
Section: Dexmedetomidine Developmentsmentioning
confidence: 99%
“…Heard et al [11 ] compared a combination of DEX/midazolam with propofol for MRI imaging. Doses employed for DEX were considerably lower (1 mg/kg bolus followed by 0.5 mg/kg/h infusion) than those used by Mason et al (above).…”
Section: Dexmedetomidine Developmentsmentioning
confidence: 99%
“…Heard ve ark.nın [12] 2008 yılında yaptığı çalışmada MRG işlemi yapılan 40 çocukta deksmedetomidin-midazolam anestezisi ile propofol anestezisi karşılaştırılmıştır. Bizim çalışmamızda premedikasyon kullanılmamıştır.…”
Section: Discussionunclassified
“…Midazolam eklenmesi çocuk hastalarda derlenme ve taburculuk sürelerini uzatmaktadır. [12,13] Sonuç olarak, MRG işlemi esnasında günü birlik anestezi verilen hastalarda son yıllarda kullanılmaya başla-nan propofolün özellikle hemodinamik değişiklikler, MRG işlemine hazır hale gelme süreleri, derlenme …”
Section: Discussionunclassified
“…A small study on 40 children undergoing magnetic resonance imaging (MRI) under general anaesthesia showed that dexmedetomidine-midazolam provides adequate anaesthesia for MRI although recovery is prolonged when compared with propofol. Heart rate was slower and systolic blood pressure was greater with dexmedetomidine when compared with propofol [49]. Moreover, Mason et al [50] concluded in their study that dexmedetomidine is a safe and effective alternative to pentobarbital for paediatric CT, being associated with a much shorter recovery time and less need for adjuvant sedatives.…”
Section: Miscellaneous Sedative Agentsmentioning
confidence: 99%