Deep eutectic solvents as novel extraction media for phenolic compounds from model oil

Abstract

Deep eutectic solvents (DES) as a new kind of green solvent were used for the first time to excellently extract phenolic compounds from model oil. It was also proved that DES could be used to extract other polar compounds from non-polar or weakly-polar solvents by liquid-phase microextraction.

Application of a computational model of natural deep eutectic solvents utilizing the COSMO-RS approach for screening of solvents with high solubility of rutin

“…These properties have led to NADES replacing ionic liquids in many applications, as the usage of ionic liquids in foods and pharmaceuticals is generally avoided nowadays because of their potential toxicity [21, 22]. The field of applications of natural deep eutectic solvents is very broad, and includes for example the dissolution of DNA [11, 12], acting as media for enzyme reactions [23], biotransformations [24], biomass processing [25], the stabilization of pigments [16], and various extractions [26–29]. The pharmaceutical industry is another field in which NADES can be extremely useful; for instance, they can be used to improve the solubility of drugs that are poorly soluble in water [30, 31] and to enhance the bioactivities of dissolved species [32].…”

Enhanced extraction of phenolic compounds using choline chloride based deep eutectic solvents from Juglans regia L.

“…Moreover, in general, these solvents have low volatility and flammability (Dai et al, 2016). The addition of water to DES, for extraction purposes, is a wellestablished procedure to reduce the viscosity of the solvents and improve the mass transfer of bioactive molecules from the natural matrices (García et al, 2016;Gu et al, 2014). Regarding temperature, its increase leads to a lower viscosity and, consequently, to higher extraction yields (Dai et al, 2016;Jancheva et al, 2017).…”

Determination of Trace Rhodamine B in Chili Oil by Deep Eutectic Solvent Extraction and an Ultra High-Performance Liquid Chromatograph Equipped with a Fluorescence Detector

“…This may be ascribed to the viscosity of the DESs which varied in the sequence DES-1 < DES-2. 25 In spite of the different extraction efficiency, the deep eutectic solvents DES-1 and DES-2 showed better selectivity for rhodamine B than some natural pigments, as displayed in UV-Vis chromatograms at 550 nm (presented in Fig. 3).…”

“…Qiu et al separated phenolic compounds from model oil using DESs as extraction media. 25 In this study, a particular, simple and cost-efficient method for the determination of trace rhodamine B in chili oil by deep eutectic solvent extraction and ultra-high-performance liquid chromatography (UPLC) equipped with a fluorescence detector was developed. The deep eutectic solvent (DES-1), 26 comprised of choline chloride and ethylene glycol (mole ratio 1:3), was used as a green and inexpensive extractant to concentrate rhodamine B from chili oil samples.…”