Deep Eutectic Solvents: An Overview of its Application as a “Green” Extractant

doi:10.20431/2349-0403.0406003

Cited by 3 publications

(2 citation statements)

References 45 publications

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“…Alternatively, mixtures of different polarity solvents were experimentally used to enhance the extraction efficiency [ [11] , [12] , [13] ] and [ 14 ]. More recently, deep eutectic solvents have been adopted as an eco-friendly alternative for phenolics extraction [ [15] , [16] , [17] , [18] , [19] ], and [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…DES are prepared by mixing two or more parent components, consisting of hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD). The advantages of DES include lower melting points, low toxicity, nonflammability, biocompatibility, and chemical tunability by varying the molar ratio of the parent components [ 18 ]. DES has been used to extract phenolic compounds from various plants, such as oranges peel [ 16 ], Moringa oleifera [ 17 ], Chlorella vulgaris [ 19 ], Rosmarinus officinalis [ 20 ], and ripe mango ( Mangifera indica L . )…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Optimization and kinetics modeling of phenolics extraction from coffee silverskin in deep eutectic solvent using ultrasound-assisted extraction

Taweekayujan,

Somngam,

Pinnarat

2023

Heliyon

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optimization and kinetics modeling of phenolics extraction from coffee silverskin in deep eutectic solvent using ultrasound-assisted extraction

Taweekayujan,

Somngam,

Pinnarat

2023

Heliyon

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A review on deep eutectic solvents: Physiochemical properties and its application as an absorbent for sulfur dioxide

Chandran

Kait

Wilfred

et al. 2021

Journal of Molecular Liquids

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Natural Deep Eutectic Solvents as Alternative Flavonoid Extractants from the Sedative Plant Composition

Dzhavakhyan

Prozhogina

Pavelieva

et al. 2022

Razrabotka i registraciâ lekarstvennyh sredstv

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Introduction. Natural deep eutectic solvents (DESs) are promising extractants for many biologically active substances from plant raw materials. They are biodegradable, safe, stable, their production is affordable and easily feasible, and the extraction efficiency is comparable to known organic solvents. In this regard, interest in deep eutectic solvents has been steadily growing in recent years, and they are being used in various fields of chemistry, pharmaceuticals and the food industry.Aim. The purpose of this work was to study the possibility of extracting flavonoids from plant raw materials using deep eutectic solvents, as well as to compare the efficiency of their extraction with traditional solvents.Materials and methods. The extraction of flavonoids was carried out from the collection of a plant composition consisting of the herb of motherwort cordial (common motherwort) (Leonurus cardiaca L.), the herb of St. John's wort (Hypericum perforatum L.), the herb of lemon balm (Melissa officinalis L.) and the herb of creeping thyme (thyme) (Thymus serpyllum L.) in a ratio of 4 : 2.5 : 2.5 : 1, crushed to a particle size of 2–3 mm. 21 eutectic solvents based on betaine hydrochloride and choline bitartrate as hydrogen bond acceptors were used as extractants.Results and discussion. The extracting ability of 21 experimental compositions of DESs was studied. The influence of the water content in the composition of DES, as well as the effect of temperature on the extraction process, has been studied. Quantitative determination of flavonoids in terms of rutin was carried out by differential spectrophotometry at a wavelength of 410 ± 2 nm. The maximum yield of flavonoids was achieved using a 40 % aqueous solution of DES based on betaine hydrochloride and propylene glycol in a molar ratio of 1 : 3 at 60 °C.Conclusion. The recovery ability of the obtained DES is comparable in efficiency and even slightly exceeds that of the classic extractant for the investigated composition – 70 % ethyl alcohol. Further development and optimization of the process of using DESs is a promising direction for the development of chemistry and pharmaceutical technology.

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Deep Eutectic Solvents: An Overview of its Application as a “Green” Extractant

Cited by 3 publications

References 45 publications

Optimization and kinetics modeling of phenolics extraction from coffee silverskin in deep eutectic solvent using ultrasound-assisted extraction

Optimization and kinetics modeling of phenolics extraction from coffee silverskin in deep eutectic solvent using ultrasound-assisted extraction

A review on deep eutectic solvents: Physiochemical properties and its application as an absorbent for sulfur dioxide

Natural Deep Eutectic Solvents as Alternative Flavonoid Extractants from the Sedative Plant Composition

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