Decreased peritoneal concentrations of interleukin-15 in women with advanced stage endometriosis

IL15 promotes growth and invasion of endometrial stromal cells and inhibits killing activity of NK cells in endometriosis

“…Differentially, the study by Lin and coworkers indicates that IL15 was decreased in PF in the advanced stage of EMS (Lin et al 2006). However, it is still unclear whether or not IL15 participates in the regulation of EMS pathogenesis by strengthening the interaction between ESCs and NK cells.…”