Decreased Mortality with Tight Glycemic Control in Critically Ill Patients: A Retrospective Analysis in a Large Community Hospital System

Joshi, Renu; Patel, Sachin; Wert, Yijin; Parvathaneni, Arvin; Cheriyath, Pramil

doi:10.4158/ep13374.or

Cited by 4 publications

(2 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Actually, the evidence from literature about glycemic thresholds in hospitalized patients is controversial [126]. These aspects have been partially investigated [127,128], mainly in the setting of the intensive care unit [129], but randomized clinical trials with a great number of patients coupling with a tight glycemic control are still lacking. diabetes warranted a better glucose control and consequently a lower rate of complications than sliding scale insulin [4].…”

Section: Transient Hyperglycemia: What To Do?mentioning

confidence: 99%

Steroid-induced hyperglycemia: An underdiagnosed problem or clinical inertia? A narrative review

Bonaventura

Montecucco

2018

Diabetes Research and Clinical Practice

View full text Add to dashboard Cite

Section: Transient Hyperglycemia: What To Do?mentioning

confidence: 99%

Steroid-induced hyperglycemia: An underdiagnosed problem or clinical inertia? A narrative review

Bonaventura

Montecucco

2018

Diabetes Research and Clinical Practice

View full text Add to dashboard Cite

“…All laboratory values were from morning fasting blood tests, which are routinely drawn between 0400 and 0630. We selected BG > 110 mg/dl to define hyperglycemia in this patient population based on studies in critical care that have shown increased risk for adverse outcomes in patients at this glycemic level (Joshi, Patel, Wert, Parvathaneni, & Cheriyath, 2014;Scuteri et al, 2014). We defined hypoglycemia as BG <70 mg/dl and increased glycemic variability as an SD of individual BG measures !29 mg/dl (Hammer et al, 2009).…”

Section: Measurementsmentioning

confidence: 99%

Glycemic Status and Infection Risk in Nondiabetic Autologous Hematopoietic Cell Transplantation Recipients

Hammer

Melkus

Casper

et al. 2016

Biological Research For Nursing

View full text Add to dashboard Cite

show abstract

The Association of Mean Plasma Glucose and In hospital Death Proportion: A Retrospective, Cohort Study of 162,169 In-Patient Data

Chen

Zhao

et al. 2021

International Journal of Endocrinology

View full text Add to dashboard Cite

Aims. To investigate the association between mean plasma glucose and inhospital death proportion. Methods. We retrospectively collected 162,169 inpatient data in Huashan Hospital from January 2012 to December 2015. Mean plasma glucose was calculated and considered as the average glycemia control during hospitalization. Patients were stratified into six groups according to mean plasma glucose. Nonlinear regression was performed to determine the associations between mean plasma glucose and inhospital death proportion, medical cost, and length of stay. Multivariate logistic regressions were performed to evaluate the relationship of mean plasma glucose and outcomes controlling for confounders including age, gender, and others. Subgroup analyses were performed on basis of whether they were surgical patients, ICU patients, patients with diabetes, or others. Results. Of the 162,169 hospitalized participants, 53.32% were male and 989 died during hospitalization. Nonlinear regression showed there were positive and significant associations between mean plasma glucose and death proportion, medical cost, and length of stay ( P < 0.001 for all). Multivariate logistic regressions showed that, compared with group B, a statistically significant association between mean plasma glucose and predicted outcome was apparent, with the odds ratios (95% confidence interval) of 5.79 (3.51–9.55), 2.85 (2.40–3.38), 6.29 (5.24–7.54), 9.34 (7.51–11.62), and 23.52 (16.64–33.26), for group A, group C, group D, group E, and group F, respectively. There was a U-shaped association between mean plasma glucose and death proportion. Subgroup analyses showed similar associations between mean plasma glucose and death proportion, medical cost, and length of stay as in the whole sample. Conclusions. There was a U-curve association between mean plasma glucose with inhospital death proportion. Mean plasma glucose was associated positively with medical cost and length of stay.

show abstract

Decreased Mortality with Tight Glycemic Control in Critically Ill Patients: A Retrospective Analysis in a Large Community Hospital System

Cited by 4 publications

References 19 publications

Steroid-induced hyperglycemia: An underdiagnosed problem or clinical inertia? A narrative review

Steroid-induced hyperglycemia: An underdiagnosed problem or clinical inertia? A narrative review

Glycemic Status and Infection Risk in Nondiabetic Autologous Hematopoietic Cell Transplantation Recipients

The Association of Mean Plasma Glucose and In hospital Death Proportion: A Retrospective, Cohort Study of 162,169 In-Patient Data

Contact Info

Product

Resources

About