Decontamination of Aflatoxins in Edible Oils: A Comprehensive Review

Javanmardi, Fardin; Khodaei, Diako; Sheidaei, Zhaleh; Bashiry, Moein; Nayebzadeh, Kooshan; Vasseghian, Yasser; Khaneghah, Amin Mousavi

doi:10.1080/87559129.2020.1812635

Cited by 35 publications

(24 citation statements)

References 88 publications

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“…Peanut is highly susceptible to the contamination of aflatoxins. Aflatoxin-contaminated peanuts pollute the environment and cause the serious economic damage [10]. Despite remarkable improvements in the technologies of harvesting and storage processing, the contamination of aflatoxins is still a problem to be solved in the peanut industry [11].…”

Section: Introductionmentioning

confidence: 99%

Recombinant Expression of Trametes versicolor Aflatoxin B1-Degrading Enzyme (TV-AFB1D) in Engineering Pichia pastoris GS115 and Application in AFB1 Degradation in AFB1-Contaminated Peanuts

Yang

Xiao

Shen

et al. 2021

Toxins

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Aflatoxins seriously threaten the health of humans and animals due to their potential carcinogenic properties. Enzymatic degradation approach is an effective and environmentally friendly alternative that involves changing the structure of aflatoxins. In this study, Trametes versicolor aflatoxin B1-degrading enzyme gene (TV-AFB1D) was integrated into the genome of Pichia pastoris GS115 by homologous recombination approach. The recombinant TV-AFB1D was expressed in engineering P. pastoris with a size of approximately 77 kDa under the induction of methanol. The maximum activity of TV-AFB1D reached 17.5 U/mL after the induction of 0.8% ethanol (v/v) for 84 h at 28 °C. The AFB1 proportion of 75.9% was degraded using AFB1 standard sample after catalysis for 12 h. In addition, the AFB1 proportion was 48.5% using AFB1-contaminated peanuts after the catalysis for 18 h at 34 °C. The recombinant TV-AFB1D would have good practical application value in AFB1 degradation in food crops. This study provides an alternative degrading enzyme for the degradation of AFB1 in aflatoxin-contaminated grain and feed via enzymatic degradation approach.

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Section: Introductionmentioning

confidence: 99%

Recombinant Expression of Trametes versicolor Aflatoxin B1-Degrading Enzyme (TV-AFB1D) in Engineering Pichia pastoris GS115 and Application in AFB1 Degradation in AFB1-Contaminated Peanuts

Yang

Xiao

Shen

et al. 2021

Toxins

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“…Therefore, AFB 1 has been classified as a class 1 carcinogen by many international authoritative organizations or institutions [ 45 , 46 ]. Due to the structural double bonds in the furan ring, AFB 1 has high carcinogenicity and toxicity [ 17 , 47 ]. The lipophilic structure of atrial fibrillation promotes its entry into the blood through gastrointestinal and respiratory tracts [ 48 , 49 ].…”

Section: Importance Of Aflatoxinsmentioning

confidence: 99%

“…and storage methods [ 15 ]. At the same time, during the production of edible oil, fresh-pressed edible oil is vulnerable to contamination of raw materials infected with Aspergillus by aflatoxin B 1 (AFB 1 ) [ 16 , 17 , 18 , 19 , 20 , 21 , 22 ]. Therefore, contamination of edible vegetable oil products by AFB 1 is a serious food safety problem ( Figure 1 ) [ 20 , 23 , 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Progress on Techniques in the Detection of Aflatoxin B1 in Edible Oil: A Mini Review

2022

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Contamination of agricultural products and foods by aflatoxin B1 (AFB1) is becoming a serious global problem, and the presence of AFB1 in edible oil is frequent and has become inevitable, especially in underdeveloped countries and regions. As AFB1 results from a possible degradation of aflatoxins and the interaction of the resulting toxic compound with food components, it could cause chronic disease or severe cancers, increasing morbidity and mortality. Therefore, rapid and reliable detection methods are essential for checking AFB1 occurrence in foodstuffs to ensure food safety. Recently, new biosensor technologies have become a research hotspot due to their characteristics of speed and accuracy. This review describes various technologies such as chromatographic and spectroscopic techniques, ELISA techniques, and biosensing techniques, along with their advantages and weaknesses, for AFB1 control in edible oil and provides new insight into AFB1 detection for future work. Although compared with other technologies, biosensor technology involves the cross integration of multiple technologies, such as spectral technology and new nano materials, and has great potential, some challenges regarding their stability, cost, etc., need further studies.

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“…Fifty grams of ground sample was weighed and transferred into a 250 mL flask. Then, 150 mL of a mixture of water and methanol (30:70; v/v) was added and placed spices, and nuts (Javanmardi et al, 2020;Khaneghah et al, 2018;Mozaffari Nejad et al, 2020).…”

Section: Extract and Cleanup Of Afmentioning

confidence: 99%

The prevalence and risk assessment of aflatoxin in sesame based products

2021

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The contamination of aflatoxins (AFs) in 120 samples of sesame seeds, tahini, and tahini halva collected from Iran’s market were evaluated. The exposed risk due to ingestion of aflatoxin B1 (AFB1) via their consumption was estimated with the aid of the Monte Carlo simulation (MCS). The highest prevalence of AF (55%) was associated with sesame seed samples, followed by tahini (45%) and tahini halva (32.5%). The AFB1 concentration in sesame seeds, tahini, and tahini halva was in the ranges of 0.21–12.35, 0.23–5.81, and 0.27–3.56 ?g/kg, respectively. The concentration of the total aflatoxin (TAF) in 7 (17.5%), 8 (20%), and 2 (5%) samples of sesame seeds, tahini, and tahini halva, respectively, was below the limit of European regulations (4 µg/kg), while the levels of AFB1 in 10 (25%), 7 (17.5%), and 6 (15%) samples of sesame seeds, tahini, and tahini halva, respectively, were higher than the European regulations (2 µg/kg). As the percentile 50 and 95 of margin of exposure (MOE) with AFB1 for sesame seed, tahini, and tahini halva was more than 10,000, it could conclude the intake of aflatoxin through the consumption of mentioned products did pose a not remarkable cancer risk for adults.

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Decontamination of Aflatoxins in Edible Oils: A Comprehensive Review

Cited by 35 publications

References 88 publications

Recombinant Expression of Trametes versicolor Aflatoxin B1-Degrading Enzyme (TV-AFB1D) in Engineering Pichia pastoris GS115 and Application in AFB1 Degradation in AFB1-Contaminated Peanuts

Recombinant Expression of Trametes versicolor Aflatoxin B1-Degrading Enzyme (TV-AFB1D) in Engineering Pichia pastoris GS115 and Application in AFB1 Degradation in AFB1-Contaminated Peanuts

Recent Progress on Techniques in the Detection of Aflatoxin B1 in Edible Oil: A Mini Review

The prevalence and risk assessment of aflatoxin in sesame based products

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