Decontamination of aflatoxin duckling feed with aqueous citric acid treatment

Effect of citric acid supplemented diets on aflatoxin degradation, growth performance and serum parameters in broiler chickens

“…Several authors have reported positive effects of certain organic acids in poultry diets (Runho et al 1997, Jin et al 1998, since acidifiers might improve poultry performance by reducing colonization of pathogenic microorganisms and toxic bacterial metabolites such as ammonia and amines (Chaveerach et al 2004). Moreover, Méndez-Albores et al (2007) have observed that citric acid degrades aflatoxins in the ration.…”

Phytoinhibition of Growth and Aflatoxin Biosynthesis in Toxigenic Fungi

“…Aqueous sodium bisulfate caused the greatest reduction in mycotoxin levels [Bata and Laszitity, 1999]. Aqueous citric acid exhibits detoxifying activity in aflatoxin B1-contaminated feeds and protects animals from chronic aflatoxin toxicity [Mendez-Albores, 2007]. The aqueous citric acid had detoxification activity in treating aflatoxin contaminated maize [Méndez-Albores et al, 2005].…”

“…A large number of chemicals can react with aflatoxins and convert them to less toxic and mutagenic compounds. These chemicals include acids, bases, oxidizing agents, bisulphites and gases [Dollear et al, 1968;Mann et al, 1970;Mendez-Albores, 2007]. The components of the neem tree (Azadirachta indica) is well known for its interference in aflatoxin biosynthesis with very little action on the fungal mycelia [Bhatnagar et al, 1988., Allameh et al, 2001 .…”

Effect of moisture content, lactic acid addition and extrusion conditions on reduction of β-aflatoxins in milled sorghum (<i>Sorghum L.</i> Moench)

“…Also, organic acids have shown in previous studies to perform a detoxifi cation function in treating afl atoxin-contaminated food/feeds (Méndez-Albores et al, 2005, 2007. These results suggest that detoxifi cation of afl atoxin B 1 (AFB 1 ) initially involves the formation of the β-keto acid structure (catalysed by the acidic medium), followed by hydrolysis of the lactone ring yielding afl atoxin D 1 (AFD 1 ), derived from decarboxylation of the lactone ring-opened form of AFB 1 , which is 450 times less mutagenic than AFB 1 and presents an 18-fold toxicity decrease.…”