Phytoinhibition of Growth and Aflatoxin Biosynthesis in Toxigenic Fungi

Allameh, Abdolamir; Ziglari, Tahereh; Rasooli, Iraj

doi:10.5772/25052

Cited by 7 publications

(17 citation statements)

References 169 publications

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“…One such mutation is suspected to occur at human P53 tumor suppression gene at codon 249, leading to the conversion of guanine (G) to thymine (T) at the third nucleotide of the codon (Murphy et al, 2006). In the presence of water, AFB 1 -8, 9-dihydrodiol is formed which reacts with serum proteins (lysine or albumin) thus informing the toxicity of aflatoxins (Allameh et al, 2011;Mycotoxin Information, 2013). According to Tiffany (2013) HBV infections are commonly associated with chronic ingestion of aflatoxins.…”

Section: Aflatoxinsmentioning

confidence: 99%

“…These toxins jeopardize food safety exceeding standards set for food for human consumption and impairing exportability of these commodities into the USA or UAE and EU with maximum allowable total aflatoxin limits of 20 ppb and 4 ppb respectively (Farag, 2008;Allameh et al, 2011;Tiffany, 2013). Consequently, Africa loses 670-750 million USD annually to EU restrictive standard for aflatoxins on cereals, dried fruits and nuts; and billions on the same issue the world over (Okello et al, 2010).…”

Section: Aflatoxinsmentioning

confidence: 99%

“…Irradiation according to Allameh et al (2011) is an effective means of controlling mycotoxins. It ensures control of moulds, insects and prolongs shelf life of treated vegetables and fruits (Farag, 2008;Arya, 2010).…”

Section: Curative Strategiesmentioning

confidence: 99%

“…Ozone is a strong disinfectant. It attacks the furo-furan ring of mycotoxins through electrophilic activity forming primary ozonoides followed by monozonoides (Allameh et al, 2011). Studies in Pakistan have shown that propionic acid (0.1-0.5%), copper sulphate (0.5-1.0%) and benzoic acid (0.1-0.5%) completely inhibited A. flavus and A. parasiticus growth .…”

Section: Chemical Controlmentioning

confidence: 99%

“…All these consequently led to the search for alternatives with minimal risks . Such novel alternative approaches according to Allameh et al (2011) should be easy to use, inexpensive, and not lead to the formation of other compounds that are still toxic, or revert to re-form the parent mycotoxin, or other harmful forms of the compound, or alter the nutritional and/or organo-leptic properties of the treated produce. One alternative that is rapidly gaining grounds in plant health management is user-accessible plant-derived fungicides for the control of toxins in crops (Fapohunda, 2013;Enyiukwu et al, 2014a).…”

Section: Chemical Controlmentioning

confidence: 99%

See 4 more Smart Citations

Mycotoxins in Stored Agricultural Products: Implications to Food Safety and Health and Prospects of Plant-derived Pesticides as Novel Approach to their Management

Enyiukwu¹,

Awurum²,

Nwaneri³

2014

GJMA

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Mycotoxins are toxic secondary metabolites from some species of Aspergillus, Fusarium Penicillium and their related fungi. Their contamination results generally in inferior quality of produce and produce end-products, food safety and ultimately barriers trans-border marketability of agro-produce. Though the presence of mycotoxigenic fungus on produce does not always translate to presence of mycotoxins; however, mycotoxins are silent killers and their effects could be submerged over a long period of time especially during intermittent exposures. These fungal toxins when ingested or inhaled participate in several metabolic dysfunctions in human and livestock systems such as immunological imbalance, cancers, allergies, abortions and in some cases death of the affected hosts. Conditions of high temperatures and relative humidity coupled with poor store standards and hygiene which characterized tropical subsistence farmsteads encourage mouldiness and mycotoxin contamination of agricultural products. The mycotoxins of most agricultural importance (aflatoxins, fumonisins, ochratoxins, trichothecenes) were enumerated in this review while their management strategies were also highlighted; with emphasis on plant-derived antimycotoxigenic interventions useable in low-input agricultural production systems of sub-Saharan Africa.

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Section: Aflatoxinsmentioning

confidence: 99%

Section: Aflatoxinsmentioning

confidence: 99%

Section: Curative Strategiesmentioning

confidence: 99%

Section: Chemical Controlmentioning

confidence: 99%

Section: Chemical Controlmentioning

confidence: 99%

See 3 more Smart Citations

Mycotoxins in Stored Agricultural Products: Implications to Food Safety and Health and Prospects of Plant-derived Pesticides as Novel Approach to their Management

Enyiukwu¹,

Awurum²,

Nwaneri³

2014

GJMA

View full text Add to dashboard Cite

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Safe Food Handling Techniques to Prevent Microbial Contamination

Mahunu,

Osei-Kwarteng,

Ogwu

et al. 2024

Food Safety and Quality in the Global South

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Health impacts of aflatoxin and control of aflatoxigenic fungi

Gelaw¹,

Biru²,

Eskeziaw³

2020

Int. J. Curr. Res. Biosci. Plant Biol.

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Aflatoxins are a group of related fungal metabolites primarily produced by Aspergillus flavus and A. parasiticus. Aflatoxin is a global food safety concern with rural subsistence farming communities in developing countries being the populations most at risk of exposure. Aflatoxin contamination is the main food safety problem for field crops produced in tropical and subtropical climate regions where high temperature and humidity promote growth and proliferation of Aspergillus spp. Foods and feeds, especially cereal grains, are susceptible to invasion by molds during pre-harvest, processing, transportation, or storage. Aflatoxins impose effects in both economic and health sectors where the crisis leads to death of human beings and animals. The most well established health effect of chronic aflatoxin exposure are hepatocellular carcinoma impaired child growth and immune suppression. To minimize the risk of aflatoxicosis, there are several physical, chemical and biological methods available, but the biological strategies are safest and well effective. Therefore, this review was aimed to show the health impact of aflatoxins and the promising strategies against aflatoxin contamination.

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Phytoinhibition of Growth and Aflatoxin Biosynthesis in Toxigenic Fungi

Cited by 7 publications

References 169 publications

Mycotoxins in Stored Agricultural Products: Implications to Food Safety and Health and Prospects of Plant-derived Pesticides as Novel Approach to their Management

Mycotoxins in Stored Agricultural Products: Implications to Food Safety and Health and Prospects of Plant-derived Pesticides as Novel Approach to their Management

Safe Food Handling Techniques to Prevent Microbial Contamination

Health impacts of aflatoxin and control of aflatoxigenic fungi

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