Decline of sexual function with age in japanese men compared with american men—results of two community-based studies

Masumori, Naoya; Tsukamoto, Taiji; Kumamoto, Yoshiaki; Panser, Laurel A.; Rhodes, Thomas; Girman, Cynthia J.; Lieber, Michael M.; Jacobsen, Steven J.

doi:10.1016/s0090-4295(99)00108-9

Cited by 103 publications

(98 citation statements)

References 19 publications

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“…This has important implications in an ageing population because the prevalence is highest in the older age groups. 1,3,8,9 This is in contrast with some studies where older age was associated with more bother 24,25 but in agreement with our earlier bother/prevalence of ED analysis. 8 There was no clearly defined time frame for the men to refer to when answering the question that we have used to assess ED status.…”

Section: Discussionsupporting

confidence: 91%

Incidence rates of erectile dysfunction in the Dutch general population. Effects of definition, clinical relevance and duration of follow-up in the Krimpen Study

et al. 2004

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This study aims to describe the incidence rate of erectile dysfunction (ED) in older men in the Netherlands according to three definitions. The influence of the duration of follow-up on the incidence rate is also explored. In a large community-based follow-up study, 1661 men aged 50-75 y completed the International Continence Society sex questionnaire and a question on sexual activity, at baseline and at a mean of 2.1 and 4.2 y of follow-up. We defined 'ED' as a report of erections with 'reduced rigidity' or worse; 'Significant_ED' as 'severely reduced rigidity' or 'no erections'; and 'Clinically_Relevant_ED' as either 'ED' reported as 'quite a problem' or 'a serious problem', or 'Significant_ED' reported as at least 'a bit of a problem'. Incidence rates of ED status were calculated in those men who completed at least one period of follow-up and were not diagnosed with prostate cancer (n ¼ 1604). For 'ED' the incidence rate (cases per 1000 person-years) is 99 and ranges over the 10-y age groups from 77 (50-59 y) to 205 (70-78 y); for 'Significant_ED' these rates were 33, 21, and 97, respectively and for 'Clinically_Relevant_ED' 28, 25, and 39, respectively. In general, incidence rates should not vary with the duration of follow-up. However, for 'ED' the 4.2 y incidence rate is about 69% of the 2.1 y incidence rate. This study presents incidence rates, for the general population, as well as based on a definition of ED that takes concern/bother into account. 'Clinically_Relevant_ED' has a lower increase in incidence with increasing age than other definitions that do not take concern/bother into account. The phenomenon of lower incidence rates with longer duration of follow-up may account for the differences in reported incidence rates between different studies. The effects of differences related to the duration of follow-up should be taken into consideration in future incidence reports.

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Section: Discussionsupporting

confidence: 91%

Incidence rates of erectile dysfunction in the Dutch general population. Effects of definition, clinical relevance and duration of follow-up in the Krimpen Study

et al. 2004

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“…However, most elderly men do not complain about dissatisfaction despite declining sexual function. 11 This discrepancy between the sexuality and satisfaction among Japanese men might influence the treatment outcome. In addition, there is a difference in the approved dose of sildenafil between Japan and other countries.…”

Section: Discussionmentioning

confidence: 99%

“…The perception of sexual function and its impact on the health-related quality of life among elderly males may differ by physique, race, site, and country. 11 Therefore, this variation may influence the different clinical outcomes of sildenafil in Japanese patients from those of other populations.…”

Section: Discussionmentioning

confidence: 99%

Outcome analysis of sildenafil citrate for erectile dysfunction of Japanese patients

et al. 2005

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The approved maximal dose of sildenafil is only 50 mg in Japan, but the impact of dose regulation on treatment outcomes has not been established. Moreover, the contributors to the efficacy in patients having an intact peripheral nervous system have not been fully elucidated. We assessed in Japanese patients the treatment outcomes of sildenafil for erectile dysfunction (ED) under regulation of the approved dose and identified factors contributing to its efficacy among those with various etiologies other than pelvic surgery. We retrospectively reviewed 196 ED patients treated with sildenafil. The overall efficacy was 70.9% (139/196), and patients with psychological problems and concomitant cardiovascular disease showed high response rates (82.4 and 87.0%, respectively). Of the 139 responders, 89.9% achieved efficacy with a dose of 25 or 50 mg. Logistic regression analysis revealed concomitant cardiovascular disease and a favorable nocturnal penile tumescence result to be independent contributors to the efficacy.

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“…ED has been shown to increase with increasing age with prevalence estimates in community-based populations ranging from less than 1 to 11% for men in their 40s to 15-79% for men 70 and over. [1][2][3][4][5][6][7][8][9][10][11][12][13] The wide variation in estimates may be partly because of the disparate definitions of ED between studies. Many of these studies focused largely on ED alone, and did not provide information on other important aspects of sexuality in men.…”

Section: Introductionmentioning

confidence: 99%

Distribution of the Brief Male Sexual Inventory in community men

et al. 2003

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The objectives of the study were to characterize male sexual functioning as related to age in community-dwelling older men. In 1989, a random sample of men aged 40-79 y (n ¼ 2115) without prior prostate surgery, prostate cancer, or other conditions known to affect voiding function (except benign prostatic hyperplasia) was invited (55% agreed) to participate in the Olmsted County Study of Urinary Symptoms and Health Status Among Men. In 1996, a previously validated male sexual function questionnaire was administered to the cohort. The questionnaire has 11 questions measuring sexual drive (two questions); erectile function (three) and ejaculatory function (two), as well as assessing problems with sex drive, erections, or ejaculation (three); and overall satisfaction with sex life (one). Each question is scored on a scale of 0-4, with higher scores indicating better functioning. Cross-sectional age-specific means ( 7 s.d.) for drive, erections, ejaculation, problems, and overall satisfaction declined from 5.2 ( 7 1.5), 9.8 ( 7 2.5), 7.4 ( 7 1.4), 10.7 ( 7 2.2), and 2.6 ( 7 1.0), respectively, for men in their 40s to 2.4 ( 7 1.6), 3.3 ( 7 3.4), 3.6 ( 7 3.2), 7.7 ( 7 3.8), and 2.1 ( 7 1.2) for men 70 y and older (all Po0.001). The cross-sectional decline in function with age was not constant, with age-related patterns differing by domain. The percentage of men reporting erections firm enough to have intercourse in the past 30 days declined from 97% (454/468) among those in their 40s to 51% (180/354) among those in their 80s (Po0.001). In age-adjusted analyses, men reporting regular sexual partners had statistically significantly higher levels of sex drive, erectile function, ejaculatory function, and overall satisfaction than those who did not report regular sexual partners. Sexual drive, erectile functioning, ejaculatory functioning, and overall sexual satisfaction in men show somewhat differing cross-sectional patterns of decline with advancing age. Active sexual functioning is maintained well into the 80s in a substantial minority of community-dwelling men.

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Decline of sexual function with age in japanese men compared with american men—results of two community-based studies

Cited by 103 publications

References 19 publications

Incidence rates of erectile dysfunction in the Dutch general population. Effects of definition, clinical relevance and duration of follow-up in the Krimpen Study

Incidence rates of erectile dysfunction in the Dutch general population. Effects of definition, clinical relevance and duration of follow-up in the Krimpen Study

Outcome analysis of sildenafil citrate for erectile dysfunction of Japanese patients

Distribution of the Brief Male Sexual Inventory in community men

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