Deciduoma, Uterus, Rat

Spontaneously Arising Tumours and Tumour-like Lesions of the Cervix and Uterus in 83 Pet Guinea Pigs ( Cavia porcellus )

“…In the rat, these lesions have been observed in response to non-specific stimuli in the non-pregnant, usually pseudopregnant, animal (Hart Elcock et al, 1987). Deciduomas have a natural lifespan and regress after several days (Mitchell and Garris, 1978).…”

“…Deciduomas have a natural lifespan and regress after several days (Mitchell and Garris, 1978). They have been found in various species of small mammals including rats, mice, hamsters and rabbits (Hart Elcock et al, 1987). Deciduoma may therefore be a proliferative lesion arising due to a non-specific stimulus of the non-pregnant uterus and focal decidualization may occur with other changes, such as genital tumours.…”

Review Article: "Mesenchymal Tumor" or "Decidual-Like Reaction"?

“…The suggestions of smooth muscle cell tumor (13) and leiomyosarcoma (6) followed, which were rejected on the basis of histomorphologic differences from smooth muscle cell tumors known in various species (5 (2,7,8,18 (2,17,18,20). Rarely, these lesions occur spontaneously in oncogenicity studies; 1 example is shown in Fig.…”

Appearance of Eosinophilic Granule Cells as Pathological Changes in the Uteri of Two Aged Virgin Donryu Rats

“…GMG cells rapidly increase in number with differentiation of the decidua or the decidual reaction, whereas they are rarely observed in any organs/tissues of virgin animals (3,5,10,11 Microscopically, the lesion in Case 1 was observed in the lower part of a unilateral uterine horn. The large cells were distributed diffusely from the mesometrial triangle to the subendometrium although they also showed foci of accumulation in the latter region (Fig.…”

“…They have distinct characteristics, being large rounded or ovoid in shape and containing numerous acidophilic granules that are positive for periodic acid-Schiff (PAS) reaction (3)(4)(5), and are derived from precursor cells in the bone marrow (9).…”