“…Despite having advantages, including economic ones, DMBRs present instability in their practical application. In addition, parameters such as cell retention time (CRT), hydraulic retention time (HRT), extracellular polymeric substances (EPS), permeate flow, and the sludge morphological properties (sedimentation, dehydration, flocculability, and hydrophobicity)-which are functions of feed, temperature, and concentration of dissolved oxygen in the medium-can negatively affect the bioprocess if not strictly controlled [28][29] . However, one of the main disadvantages observed in membrane systems is the phenomenon called fouling, defined as the unwanted deposition of particles, colloids, macromolecules, and salts on the membrane surface (external fouling) and/or inside its pores (internal fouling), which causes the reduction of flow through the membrane, and consequently, a reduction in performance of the process 2, 31-32 .…”