Decade Long Survey of Low-level Laser Therapy/Photobiomodulation (LLLT/PBM) Therapy for Oral Mucositis Treatment

Abstract

Low-level laser therapy or photobiomodulation (LLLT/PBM) therapy has been widely applied to enhance and accelerate the recovery of oral mucositis. This study investigates the documented effect of LLLT on oral mucositis caused by chemotherapy. This review appraises 6 animal studies and 12 clinical studies published in the Pubmed database during the past 10 years, related to the application of LLLT for the treatment of mucositis. Despite varied parameters and diverse conditions, the assessed articles indicate that application of LLLT on oral mucositis using near-infrared wavelengths is prophylactic, reduces pain, and enables a rapid recovery. Various combined treatments were also identified among the published papers, which further establishes the efficacy of LLLT as a viable treatment.

Clinical applications of diode lasers in dentistry - Case series with review of literature

“…A number of cases have been successfully treated with laser in dentistry, which is shown in Table 1 . [2][3][4][5][6] Lasers that can be used for excision include the CO2 laser, the Erbium: YAG laser, the Neodymium: YAG laser, and the diode laser. 7 The advantages of laser therapy include minimal bleeding, decreased post-operative pain, faster wound healing, no edema, and the exclusion of sutures.…”

Application of photobiomodulation therapy in the recovery of a fracture model in different countries: a concise review

“…The overall mechanism of PBM is that photons that are absorbed by the target tissue are converted to useful energy which enhances the metabolic processes in the cell, such as the elevation of adenosine triphosphate (ATP) and reactive oxygen species (ROS) production [24,25]. First, PBM delivers photons to the mitochondria of the cell.…”