Death due to chikungunya

Bandyopadhyay, Bhaswati; Bandyopadhyay, Debasish; Bhattacharya, Rana; De, Rajyasree; Saha, Bibhuti; Mukherjee, H; Hati, Amiya Kumar

doi:10.1258/td.2008.080382

Cited by 6 publications

(5 citation statements)

References 2 publications

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“…In the largest report of children diagnosed with TRALI, the age of reported TRALI cases ranged between 2 and 17 years of age. A potential explanation for the discrepancy in this study is that children in this age group are unique with different underlying pathophysiology; however, this is not supported by previous case reports . It is more likely that children of this age were under recognized by physicians.…”

Section: Discussioncontrasting

confidence: 89%

Transfusion‐related lung injury in children: a case series and review of the literature

Lieberman

Petraszko

et al. 2013

Transfusion

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This study is the largest case series of reported TRALI cases in children. Crude modeling suggests that the incidence of TRALI in children is similar to that of adults. Although the numbers are small, there do not appear to be differences in presentation or outcome between adults and children with TRALI. TRALI is associated with significant morbidity and mortality and pediatricians need to consider this diagnosis in children who experience respiratory distress after transfusions.

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Section: Discussioncontrasting

confidence: 89%

Transfusion‐related lung injury in children: a case series and review of the literature

Lieberman

Petraszko

et al. 2013

Transfusion

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“…However, there have been reports of mortality due to Chikungunya fever during the present epidemic in some publications. [44668485] Mavalankar et al . [85] compared the mortality rates in 2006 with those in 2002-2005 for Ahmedabad and found that 2,944 excess deaths occurred during the Chikungunya epidemic (August-November 2006) when compared with the average number of deaths in the same months during the preceding 4 years.…”

Section: Mortalitymentioning

confidence: 99%

Epidemiology, clinical manifestations, and diagnosis of chikungunya fever: Lessons learned from the re-emerging epidemic

et al. 2010

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Chikungunya fever, caused by “Chikungunya virus,” is an arbovirus disease transmitted by the bite of infected mosquitoes belonging to the genus Aedes. Chikungunya fever epidemics have been reported from several countries around the world. The disease that was silent for nearly 32 years re-emerged in the October 2005 outbreak in India that is still ongoing. The incubation period ranges from 3 to 12 days. The onset is usually abrupt and the acute stage is characterized by sudden onset with high-grade fever, severe arthralgias, myalgias, and skin rash. Swollen tender joints and crippling arthritis are usually evident. In the chronic stage, relapses that include sensation of fever, asthenia, exacerbation of arthralgias, inflammatory polyarthritis, and stiffness may be evident. Neurological, ocular, and mucocutaneous manifestations have also been described. Chronic arthritis may develop in about 15% of the patients. Viral culture is the gold standard for the diagnosis of Chikungunya fever. Reverse transcription polymerase chain reaction and real-time loop-mediated isothermal amplification have also been found to be useful. Serodiagnostic methods for the detection of immunoglobulin M and immunoglobulin G antibodies against Chikungunya virus are more frequently used. Chikungunya is a self-limiting disease; however, severe manifestations such as meningoencephalitis, fulminant hepatitis, and bleeding manifestations may sometimes be life-threatening. Treatment is symptomatic and supportive. Prevention by educating the community and public health officials, vector control measures appear to be the best approach at controlling Chikungunya fever as no commercially available vaccine is available for public use in India for this condition presently.

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“…0.738 deaths/100,000 population (in North Santander department) ( Table 1). As stated by de la Hoz et al [2], previous studies in other continents have reported fatal and severe CHIK [4][5][6][7]. Although fatal cases have not been reported in some important epidemics around the globe, an increased mortality during CHIK outbreaks has been highlighted in countries such as India [8,9] and, in Reunion Island where a CFR of 10.7-27.7% and about 1 death/100,000 population mortality were reported during the 2005-2006 epidemics [10,11].…”

mentioning

confidence: 99%