Death as a Drug Side Effect in FAERS: Is Glyphosate Contamination a Factor?

Abstract

An analysis of selected datasets from the FDA's drug Adverse Event Reporting System (FAERS) leads us to hypothesize that glyphosate contamination in both food and drugs is a major contributor to chronic and acute kidney failure respectively. In chronic kidney failure, glyphosate-induced pancreatitis results in the release of trypsin, causing a leaky vasculature. The albumin-bound glyphosate escapes into the tissues, protecting the circulatory system and kidneys but resulting in multiple symptoms related to skin, gut, brain, bones, lungs, etc. The rare and poorly understood acute kidney failure response reported for protamine sulfate and Trasylol ® is strikingly similar to that associated with glyphosate poisoning. Both drugs are derived from biological tissues that are plausibly contaminated with glyphosate. These drugs protect from haemorrhage, which leads to retention of glyphosate in the vasculature, are followed by circulatory collapse and a high likelihood of death as an outcome. We support our argument by comparing symptom profiles of selected subsets of FAERS with those related to glyphosate poisoning, anomalous reactions to protamine sulfate, and conditions showing strong statistical time-trend correlations with glyphosate.

Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of Pathology Linked to G6PD Deficiency and Sulfomucins

“…If a drug or symptom occurred much more frequently in one dataset over another, an association was suspected and a method of quantifying the discrepancy was formulated. A 95% confidence interval (CI) was determined for each parameter we investigated according to methods described in [ 32 ]. Only results that are significant to the 95% CI are reported.…”

“…Following [ 32 ], we devised a simple scoring scheme to capture the degree of skew between the two datasets for a given drug or symptom. In particular, we need to know the frequency of occurrence for a given drug or symptom.…”

Uso de Equipamentos de Proteção Individual e Análise do glifosato em propriedades rurais do Espírito Santo

“…Sabe-se que na flora normal do corpo humano encontram-se bactérias que auxiliam em algumas funções fisiológicas, como, por exemplo, as presentes no intestino. Essas possuem a mesma via que o herbicida glifosato inibe, e assim, quando eliminadas, deixam espaço para outros agentes patogênicos causarem infecções (SENEFF, 2015).…”

“…Os sintomas mais comuns são diminuição da temperatura corporal e da atividade espontânea, hipertermia, hipotensão, irritações em geral no local de contato com o agente tóxico, dor abdominal, náuseas, vômitos, destruição dos glóbulos vermelhos no sangue e até desmaios (OGA, 2008;MORAES, 2010). Os maiores agravos do glifosato são seus efeitos crônicos, que são: perda de peso, desordem digestiva, ulcerações graves, pneumonias, danos hepáticos e renais, problemas na reprodução, alterações nas células placentárias, Alzheimer, autismo e mutações carcinogênicas que não são corrigidas pelos pontos de checagem do ciclo celular e da mitose que induzem neoplasias CASTRO;HISSA, 2008;FERREIRA, 2013, SENEFF, 2014SENEFF, 2015).…”