De novo strategy with engineering a multifunctional bacterial cellulose-based dressing for rapid healing of infected wounds

Zhou, Chen; Yang, Zhi-Fei; Xun, Xiaowei; Ma, Le; Chen, Zejing; Hu, Xiaoming; Wu, Xidong; Wan, Yizao; Ao, Haiyong

doi:10.1016/j.bioactmat.2021.10.043

Cited by 36 publications

(20 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The combination of bacterial cellulose, in a dressing, exhibited favorable antibacterial activities and no cytotoxicity [ 167 ]. Zhou et al [ 168 ] demonstrated that their bacterial cellulose bandage associated with collagen I and hydroxypropyltrimethyl ammonium chloride chitosan exhibited excellent antibacterial activity, cytocompatibility and promoted the growth and proliferation of NIH3T3 cells and HUVECs cells. Silver nanoparticles and polydopamine incorporated into bacterial cellulose demonstrated antibacterial activity, increased cell viability, showed no cytotoxicity to fibroblast cells, granulation tissue formation, angiogenesis and re-epithelialization upon histopathological examination [ 169 ].…”

Section: Hydrogel: Decellularized Extracellular Matrix and Cellulosementioning

confidence: 99%

Bacterial Cellulose and ECM Hydrogels: An Innovative Approach for Cardiovascular Regenerative Medicine

Silva

Pantoja

Almeida

et al. 2022

IJMS

View full text Add to dashboard Cite

Cardiovascular diseases are considered the leading cause of death in the world, accounting for approximately 85% of sudden death cases. In dogs and cats, sudden cardiac death occurs commonly, despite the scarcity of available pathophysiological and prevalence data. Conventional treatments are not able to treat injured myocardium. Despite advances in cardiac therapy in recent decades, transplantation remains the gold standard treatment for most heart diseases in humans. In veterinary medicine, therapy seeks to control clinical signs, delay the evolution of the disease and provide a better quality of life, although transplantation is the ideal treatment. Both human and veterinary medicine face major challenges regarding the transplantation process, although each area presents different realities. In this context, it is necessary to search for alternative methods that overcome the recovery deficiency of injured myocardial tissue. Application of biomaterials is one of the most innovative treatments for heart regeneration, involving the use of hydrogels from decellularized extracellular matrix, and their association with nanomaterials, such as alginate, chitosan, hyaluronic acid and gelatin. A promising material is bacterial cellulose hydrogel, due to its nanostructure and morphology being similar to collagen. Cellulose provides support and immobilization of cells, which can result in better cell adhesion, growth and proliferation, making it a safe and innovative material for cardiovascular repair.

show abstract

Section: Hydrogel: Decellularized Extracellular Matrix and Cellulosementioning

confidence: 99%

Bacterial Cellulose and ECM Hydrogels: An Innovative Approach for Cardiovascular Regenerative Medicine

Silva

Pantoja

Almeida

et al. 2022

IJMS

View full text Add to dashboard Cite

show abstract

“…Cellulose-modified organic nanocomposite exhibits high performance as a wound dressing. A Three-dimensional (3D) network of collagen I (Col-I), hydroxypropyl trimethyl ammonium chloride chitosan (HACC), and BC was prepared via membrane-liquid interface (MLI) method [212]. HACC offered antibacterial activity during wound healing [212].…”

Section: Cellulose Nanoparticles For Wound Dressingmentioning

confidence: 99%

“…A Three-dimensional (3D) network of collagen I (Col-I), hydroxypropyl trimethyl ammonium chloride chitosan (HACC), and BC was prepared via membrane-liquid interface (MLI) method [212]. HACC offered antibacterial activity during wound healing [212]. Inerpan (a polymer of L-leucine and methyl L-glutamate) and Procel-Super (SOD) accelerated the healing of burn wounds for BC-based wound dressing by 17.0 and 5.5%, respectively [213].…”

Section: Cellulose Nanoparticles For Wound Dressingmentioning

confidence: 99%

A Review on Cellulose-based Materials for Biomedicine

Abdelhamid¹,

Mathew²

2022

Preprint

View full text Add to dashboard Cite

There are various biomaterials in nature, but none fulfills all the requirements. Cellulose, eco-friendly material-based biopolymers, have been advanced biomedicine to satisfy most market demand and circumvent many ecological concerns. This review aims to present an overview of the state of the art in cellulose's knowledge and technical biomedical applications. It included an extensive bibliography of recent research findings for fundamental and applied investigations. The chemical structure of cellulose allows modifications and simple conjugation with several materials, including nanoparticles, without tedious efforts. Cellulose-based materials were used for biomedicine applications such as antibacterial agents, antifouling, wound healing, drug delivery, tissue engineering, and bone regeneration. They advanced the applications to be cheap, biocompatible, biodegradable, easy for shaping and processing into different forms, with suitable chemical, mechanical and physical properties.

show abstract

“…Bacterial cellulose (BC), one type of interpenetrating polymer composed of 100% cellulose, is widely studied in terms of culturing and in applications such as biomedical [ 1 , 2 , 3 , 4 , 5 , 6 ], composites [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 ], environmental remediation [ 16 , 17 , 18 , 19 , 20 , 21 ], tissue engineering [ 22 , 23 , 24 ], pharmaceutical [ 25 , 26 , 27 , 28 ], packaging [ 29 , 30 , 31 ], textiles [ 32 , 33 , 34 ], and catalysts [ 35 ]. Due to a networked nanofibrous structure, BC can be fabricated into various forms including hydrogels, aerogels, and films.…”

Section: Introductionmentioning

confidence: 99%

“…SCOBY BC can be molded into various sizes and forms depending on the culture container. Since BC hydrogel has the ability to absorb and retain liquid about 40–50 times its own weight [ 1 ], it has gained much attention in the fields of biomedical, tissue engineering, and pharmaceutical applications. The advantage of BC dressing compared to gauzes is that it is non-adherent and easy to peel off without pain.…”

Section: Introductionmentioning

confidence: 99%

Chitosan-Coated Bacterial Cellulose (BC)/Hydrolyzed Collagen Films and Their Ascorbic Acid Loading/Releasing Performance: A Utilization of BC Waste from Kombucha Tea Fermentation

et al. 2022

View full text Add to dashboard Cite

SCOBY bacterial cellulose (BC) is a biological macromolecule (considered as a by-product) that grows at the liquid–air interface during kombucha tea fermentation. In this study, BC:HC (hydrolyzed collagen) blend films coated with 1 wt% chitosan (CS) were loaded with ascorbic acid to study loading/releasing performance. At first, the mechanical properties of the blend films were found to be dependent on HC ratio. After chitosan coating, the coated films were stronger due to intermolecular hydrogen bonding interaction and the miscibility of two matrixes at the interface. The antibacterial activity test according to the AATCC Test Method revealed that chitosan-coated BC/HC films exhibited excellent antimicrobial activity against S.aureus growth from the underneath and the above film when compared to BC and BC:HC films. Moreover, chitosan was attractive to ascorbic acid during drug loading. Consequently, its releasing performance was very poor. For BC:HC blend films, ascorbic acid loading/releasing performance was balanced by water swellability, which was controlled using blending formulation and coating. Another advantage of BC films and BC:HC blend films was that they were able to maintain active ascorbic acid for a long period of time, probably due to the presence of plenty of BC hemiacetal reducing ends (protective group).

show abstract

De novo strategy with engineering a multifunctional bacterial cellulose-based dressing for rapid healing of infected wounds

Cited by 36 publications

References 63 publications

Bacterial Cellulose and ECM Hydrogels: An Innovative Approach for Cardiovascular Regenerative Medicine

Bacterial Cellulose and ECM Hydrogels: An Innovative Approach for Cardiovascular Regenerative Medicine

A Review on Cellulose-based Materials for Biomedicine

Chitosan-Coated Bacterial Cellulose (BC)/Hydrolyzed Collagen Films and Their Ascorbic Acid Loading/Releasing Performance: A Utilization of BC Waste from Kombucha Tea Fermentation

Contact Info

Product

Resources

About