DCE-Net: A Dynamic Context Encoder Network for Liver Tumor Segmentation

Abstract

Segmentation of a tumor region from medical images is critical for clinical diagnosis and the planning of surgical treatments. Recent advancements in machine learning have shown that convolutional neural networks are powerful in such image processing while largely reducing human labor. However, the variant shapes of liver tumors with blurred boundaries in medical images cause a great challenge for accurate segmentation. The feature extraction capability of a neural network can be improved by expanding its architecture, but it inevitably demands more computing resources in training and hyperparameter tuning. This paper presents a Dynamic Context Encoder Network (DCE-Net), which incorporated multiple new modules, such as the Involution Layer, Dynamic Residual Module, Context Extraction Module, and Channel Attention Gates, for feature extraction and enhancement. In the experiment, we adopted a liver tumor CT dataset of LiTS2017 to train and test the DCE-Net for liver tumor segmentation. Experimental results showed that the precision, recall, Dice, and AUC were 0.8961, 0.9711, 0.9270, and 0.9875, respectively, outperforming other state-of-the-art networks. Furthermore, our ablation study shows that the accuracy and training efficiency are markedly superior to those networks without involution or dynamic residual modules. Therefore, the proposed DCE-Net has potential for the automatic segmentation of liver tumors in clinical settings.

A Quantitative Multiparametric MRI Analysis Platform for Estimation of Robust Imaging Biomarkers in Clinical Oncology

“…All major MRI vendors have tools for DCE MRI semi-quantitative analysis or Standard Tofts (e.g., NordicICE; Nordic Neuro Lab, Bergen, Norway). Currently, a selection of open-source tools exists for time-course compartmental models or basic Tofts analysis of DCE data (e.g., Madym [22], MITK-ModelFit [55], FireVoxel (https://firevoxel.org/, accessed on 10 October 2023), DCENET [56]). DW MRI tools for monoexponential ADC modeling are widely available on all major MRI vendor platforms.…”