Data. I

Hacker, Robert J.; Krall, John M.; Fox, John L.

doi:10.1007/978-1-4612-5437-9_3

Intracranial Aneurysms 1983

DOI: 10.1007/978-1-4612-5437-9_3

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Data. I

Robert J. Hacker¹,

John M. Krall²,

John L. Fox³

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1989

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Cited by 5 publications

References 81 publications

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Pattern of Cerebral Aneurysms in Morocco: Review of the Concept of Their Rarity in Developing Countries: Report of 200 Cases

et al. 2001

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Some data in this study (the delay between subarachnoid hemorrhage and admission, the high incidence of urban patients [80%], and the high rate of giant aneurysms) explain why many cases of ruptured aneurysms are not diagnosed. The analysis of our clinical series and the results of the epidemiological surveys show that the incidence has doubled every 5 years. These findings confirm that cerebral aneurysms are not rare in Morocco. A critical reading of the published articles claiming a low incidence of cerebral aneurysms in Africa, the Middle East, and Asia shows that this conclusion is not based on accurate and reliable statistical studies. Neurosurgeons in these regions should abandon this idea of rarity, and they should search for arterial cerebral aneurysms and develop the optimum conditions for the treatment of patients with aneurysms.

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Pattern of Cerebral Aneurysms in Morocco: Review of the Concept of Their Rarity in Developing Countries: Report of 200 Cases

et al. 2001

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Risk factors in intracranial saccular aneurysms Aspects on the formation and rupture of aneurysms, and development of cerebral vasospasm

Østergaard

1989

Acta Neurologica Scandinavica

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Intracranial saccular aneurysms have been a well-known clinical and pathological entity for over two centuries. The pathophysiological events that lead to aneurysm formation and rupture are, however, poorly understood. Besides an HLA-associated genetic factor, the most widely accepted risk factors are arterial hypertension, female gender, and increasing age. Some aneurysm patients have a deficient formation of Type III collagen. This seems to interfere with the mechanical integrity of the cerebral arterial wall encouraging aneurysm formation. While some of the risk factors may be involved in the process of aneurysm formation, others may be of importance in the actual aneurysm rupture. Medical and surgical developments have only had a slight impact on mortality rates from aneurysm rupture. The principal cause of death and disability is cerebral arterial spasm. Considerable effort has been expended in investigating the etiology of this phenomenon. Previous studies have failed to yield conclusive evidence of the causative agent(s) or the nature of cerebral artery narrowing. The time course of vasospasm after the onset of subarachnoid hemorrhage is consistent with an immune-mediated response, and more recent observations suggest that immunological processes including activation of the complement system may be involved. Missed minor bleeding episodes may thus be a risk factor for aneurysm patients in respect to the development of cerebral vasospasm.

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Angiographic frequency of saccular intracranial aneurysms in patients with spontaneous cervical artery dissection

Schievink

Mokri²,

Piepgras³

1992

Journal of Neurosurgery

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The pathogenesis of intracranial aneurysms and spontaneous cervical artery dissection is incompletely understood but a primary arteriopathy, possibly similar in both disorders, may be of importance. To investigate the frequency of intracranial aneurysms in patients with spontaneous cervical artery dissection, the angiograms of 164 patients who were diagnosed at the Mayo Clinic as having spontaneous extracranial carotid or vertebral artery dissection were reviewed. Thirteen intracranial aneurysms were detected in nine (5.5%) of the 164 patients: eight (8.8%) of the 91 female patients and one (1.4%) of the 73 male patients. The frequency of intracranial aneurysms in these patients was significantly higher (p less than 0.01) than that observed in a recent angiographic study from the same institution, estimating the frequency of intracranial aneurysms in the general population (1.1%). The significance of these findings is discussed.

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Data. I

Cited by 5 publications

References 81 publications

Pattern of Cerebral Aneurysms in Morocco: Review of the Concept of Their Rarity in Developing Countries: Report of 200 Cases

Pattern of Cerebral Aneurysms in Morocco: Review of the Concept of Their Rarity in Developing Countries: Report of 200 Cases

Risk factors in intracranial saccular aneurysms Aspects on the formation and rupture of aneurysms, and development of cerebral vasospasm

Angiographic frequency of saccular intracranial aneurysms in patients with spontaneous cervical artery dissection

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