Das Druckvolumdiagramm des Warmblüterherzens

The ventricular pressure-volume diagram revisited.

“…The relative increase or decrease in peak isovolumic pressure allows one to quantify the alteration in ventricular contractility by neural (reflex) and humoral agents. 33 ' 34 However, there has been no way to translate the measured change in this isovolumic pressure index into changes in stroke volume, endsystolic volume, and end-systolic pressure to be expected of a given ejecting ventricle.…”

A comparison of left ventricular volume-pressure relations of excised perfused canine hearts in isovolumic contraction, arrest and fibrillation.

“…(Diamond et al 1971;Gaasch et al 1972;Fester and Samet 1974;Crossman and McLaurin 1976;Mirsky 1976). Although hysteresis has been acknowledged in the LV (Ullrich et al 1954;) diastolic v-p relations of the deflation phase has not been analyzed quantitatively, while those of inflation have been mainly investigated (Monroe and French 1960;Laks et al 1967;Taylor et al 1967a;Hood et al 1970;Powell at al. 1970;Diamond et al 1971;Romero et al 1972).…”

“…It has been noted that there are viscoelastic properties not only in skeletal muscle but also in papillary muscle (Alexander 1962;Hoffman et al 1968;Little 1969;Pinto and Fung 1973;Grossman and McLaurin 1976), and hysteresis characteristics inherent to its material has been presented in the left ventricle (LV) (Ullrich et al 1954;. On the heart muscle, however, many investigators have not considered viscous element to play an important role except for the case of high output induced by isoproterenol infusion (Noble et al 1969) or a less compliant ventricle in pathological state (Gaasch et al 1975), although there are still some controversies for this point (Grossman and McLaurin 1976;Rankin et al 1977).…”

The step response of left ventricular pressure to ejection flow: A system oriented approach

“…However, there is a general agreement that such models should be as simple as possible in order to optimally compress information present in the measurements into useful empirical relationships (2,5,7,14,20,25,26,29,48,85,87,108,109). This parametrization, which has a long history (39,82,100), has led to the proposal of a number of contractility indices (3,40,63,68), several of which enjoyed some physiological and even clinical popularity for some time.…”

“…An index widely accepted is ventricular elastance, introduced by Suga, 1969 (93), who concluded a longer history of investigations (67,100). Its usefulness is based on the fact that under certain restrictions, during ventricular ejection, there is a unique, instantaneous, nearly linear relation between ventricular volume and ventricular pressure (95); according to the equation:…”