Dare/Physbe

Korn, Granino A.; McLeod, John; Wait, John V.

doi:10.1177/003754977001500507

Cited by 13 publications

(4 citation statements)

References 3 publications

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“…Similarly, stability analysis has been done for remaining phases of a cardiac cycle. As per the Lyapunov's stability criteria, system described by (2) is found to be stable over the different phases.…”

Section: Ventricular Elastance Versus Time Plot Is Shown Inmentioning

confidence: 99%

“…The stability analysis has been done for the cardiovascular system. Lyapunov's second method has been used for the linear time varying system presented by (2). A few sample calculations for an isovolumic phase are shown as follows.…”

Section: Stability Issuesmentioning

confidence: 99%

“…Further, Windkessel theory was formally developed by German physiologist Otto Frank [1]. After the development of analog computers, PHYSBE became a popular benchmark in cardiovascular modeling [2]. Around mid-1970s, the digital computer brought a revolution in the modeling.…”

Section: Introductionmentioning

confidence: 99%

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Stability issues in a cardiovascular circulation

Jain

Pal

Maka

2014

Proceedings of the 2014 IEEE Students' Technology Symposium

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Modeling of physiological systems is useful for qualitative and quantitative explanation of the underlying physiological mechanisms. Cardiovascular system has been chosen for the study. The 5 th order time varying state space model for the cardiovascular system has been simulated. Considering cardiovascular circulation to be a switched linear time varying system, the stability issues in the same have been addressed.

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Section: Ventricular Elastance Versus Time Plot Is Shown Inmentioning

confidence: 99%

Section: Stability Issuesmentioning

confidence: 99%

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Stability issues in a cardiovascular circulation

Jain

Pal

Maka

2014

Proceedings of the 2014 IEEE Students' Technology Symposium

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“…Several simulations of the cardiovascular system have been presented previously. An earlier simulation known as PHYSBE provided a lumped parameter, nonlinear system to represent the flow of blood, and its properties such as heat, throughout the circulatory system (Korn et al, 1970). This simulation was later converted into a SIMULINK model.…”

Section: Introductionmentioning

confidence: 99%

Simulation and enhancement of a cardiovascular device test rig

Gregory

Greatrex

Timms

et al. 2010

Journal of Simulation

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Cardiovascular assist devices are tested in mock circulation loops (MCLs) prior to animal and clinical testing. These MCLs rely on characteristics such as pneumatic parameters to create pressure and flow, and pipe dimensions to replicate the resistance, compliance and fluid inertia of the natural cardiovascular system. A mathematical simulation was developed in SIMULINK to simulate an existing MCL. Model validation was achieved by applying the physical MCL characteristics to the simulation and comparing the resulting pressure traces. These characteristics were subsequently altered to improve and thus predict the performance of a more accurate physical system. The simulation was successful in simulating the physical MCL, and proved to be a useful tool in the development of improved cardiovascular device test rigs.

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