Daniel Carrion’s experiment: the use of self-infection in the advance of medicine

Og, Pamo

doi:10.4997/jrcpe.2012.119

Cited by 2 publications

(1 citation statement)

References 7 publications

(4 reference statements)

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“…A transient immunosuppressive state has been described during the acute phase of the infection by B. bacilliformis [18]. Complete blood count may show a discrete lymphopenia associated with a significant decrease in TCD4+ lymphocytes with an inversion of the TCD4+/TCD8+ ratio [19].…”

Section: Discussionmentioning

confidence: 99%

Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru

et al. 2017

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Objective: This study investigated an outbreak of Bartonellosis in a coastal region in Peru.Results: A total of 70 (n = 70) samples with clinical criteria for the acute phase of Bartonellosis and a positive peripheral blood smear were included. 22.85% (n = 16) cases of the samples were positive for Bartonella bacilliformis by PCR and automatic sequencing. Of those positive samples, 62.5% (n = 10) cases were positive only for B. bacilliformis and 37.5% (n = 6) cases were positive to both Mycobacterium spp. and B. bacilliformis. The symptom frequencies were similar in patients diagnosed with Carrion's disease and those co-infected with Mycobacterium spp. The most common symptoms were headaches, followed by malaise and arthralgia.

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Section: Discussionmentioning

confidence: 99%

Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru

et al. 2017

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Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?

Mazulis

Weilg

Alva-Urcia

et al. 2015

Asian Pacific Journal of Tropical Medicine

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Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage prevention. Erythrocytes have a predisposition towards oxidized environments due to their lack of mitochondria, giving G6PD a major role in its stability. G6PD deficiency (G6PDd) is the most common enzyme deficiency in humans; it affects approximately 400 million individuals worldwide. The overall G6PDd allele frequency across malaria endemic countries is estimated to be 8%, corresponding to approximately 220 million males and 133 million females. However, there are no reports on the prevalence of G6PDd in Andean communities where bartonellosis is prevalent.

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Daniel Carrion’s experiment: the use of self-infection in the advance of medicine

Cited by 2 publications

References 7 publications

Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru

Co-infection with Bartonella bacilliformis and Mycobacterium spp. in a coastal region of Peru

Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?

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