Danger of sputum purulence screens in culture of Legionella species

Ingram, John G.; Plouffe, Joseph F.

doi:10.1128/jcm.32.1.209-210.1994

Cited by 48 publications

(15 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…All the collected sputum samples were cultured, as sputum from LD – patients often do not fulfill the routine microscopic criteria for representative lower airway samples . This means that some non‐representative lower airway samples might have been analysed.…”

Section: Discussionmentioning

confidence: 99%

Aetiology and risk factors of community‐acquired pneumonia in hospitalized patients in Norway

Røysted

Simonsen

Jenkins

et al. 2015

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Aetiology and risk factors of community‐acquired pneumonia in hospitalized patients in Norway

Røysted

Simonsen

Jenkins

et al. 2015

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

“…Most laboratories also report an improvement in the quality of specimens once these standards are imposed. Two caveats regarding the use of these criteria are that cytologic screening is not appropriate for studies of Legionella spp [34] or acid-fast bacilli, and specimens obtained using hypertonic saline (induced sputum) generally provide inadequate specimens because of high concentrations of SECs [35].…”

Section: Cellular Analysis As a Contingency For Culturementioning

confidence: 99%

Diagnostic test for etiologic agents of community-acquired pneumonia

Bartlett

2004

Infectious Disease Clinics of North America

View full text Add to dashboard Cite

Diagnostic tests for the detection of the etiologic agent of pneumonia are neither recommended nor done for most outpatients with CAP (Table 4).Most of these patients have no clear diagnosis but seem to do well with empiric antibiotic treatment, which often costs less than the diagnostic tests. For hospitalized patients, a pre-treatment blood culture and an expectorated sputum gram stain and culture should be done. Testing for Legionella spp is appropriate in hospitalized patients, especially those who are seriously ill. New tests that merit use in selected patients are the urinary antigen assay for S pneumoniae and the PCR test for L pneumophila. Anticipated developments in the near future are PCR tests for detection of C pneumoniae and M pneumoniae.

show abstract

“…Nonpurulent sputum with few polymorphonuclear leukocytes and numerous squamous epithelial cells are traditionally considered to be inadequate specimens for cultures; however, many such specimens have yielded L. pneumophila by culture. 25,40…”

Section: Culturementioning

confidence: 99%

Legionella as a Cause of Severe Pneumonia

Vergis

Akbaş²,

Yu³

2000

Seminars in Respiratory and Critical Care Medicine

View full text Add to dashboard Cite

Legionella pneumophila has been found to be a common cause of community-acquired pneumonia in patients who required intensive care unit (ICU) admission. In many studies, the clinical manifestations for Legionnaires' disease were more severe and the mortality was higher when compared with pneumonias of other etiology. However, this may be due to delay in diagnosis and suboptimal antibiotic therapy, rather than enhanced virulence of L. pneumophila. A syndromic approach using high fever, diarrhea, mental status changes, hyponatremia, etc., may be useful in suggesting the correct diagnosis in patients with severe pneumonia, but this remains to be validated. The availability of Legionella diagnostic microbiology testing in-house (rather than being sent to an outside reference laboratory) maximizes the ability to correctly diagnose Legionnaires' disease. All patients with community-acquired pneumonia admitted to an ICU should undergo Legionella testing using the urinary antigen and culture on selective media. Moreover, we recommend routine cultures of the hospital water supply once a year (regardless of whether a case of nosocomial Legionnaires' disease has ever been diagnosed). If Legionella is found in the water supply, all patients with nosocomial pneumonia should undergo diagnostic tests for Legionella; empiric anti-Legionella antibiotics should be administered pending definitive diagnosis.

show abstract

Danger of sputum purulence screens in culture of Legionella species

Cited by 48 publications

References 6 publications

Aetiology and risk factors of community‐acquired pneumonia in hospitalized patients in Norway

Aetiology and risk factors of community‐acquired pneumonia in hospitalized patients in Norway

Diagnostic test for etiologic agents of community-acquired pneumonia

Legionella as a Cause of Severe Pneumonia

Contact Info

Product

Resources

About