This article examines whether the importance of parents, siblings, best friends, and romantic interests are sex-specific in predicting daily juvenile smoking. Juveniles who smoke daily are strongly influenced by prosmoking attitudes and behaviors of same-sex family members. However, peers remain the most important associations in predicting daily smoking. An important finding is that juveniles without same-sex family role models, or close peers, are at higher risk. Policy implications for prevention and cessation programs are discussed.