Czy istnieje różnica w jakości życia i występowaniu objawów psychiatrycznych u chorych na akromegalię i inne choroby przewlekłe?

Abstract

Psychiatric morbidity, mainly anxiety and insomnia, occurs in 50% of patients with acromegaly. However, the psychological wellbeing and mood seem to be related to other factors such as the acceptance of the illness. Thus, concerning the diagnosis, treatment, and monitoring of acromegaly an interdisciplinary approach, taking into account psychological and psychiatric consultation, is needed.

Executive functioning and quality of life in acromegaly

“…Subjects with acromegaly showed more visible physical effect including hypertension, polyarthralgia, osteoporosis, and kyphosis. Similar results were reported by Webb et al, but not Szcześniak et al, who reported worse social relationships than the general population 18,22,23…”

Importance of Illness Acceptance Among Other Factors Affecting Quality of Life in Acromegaly

“…However, it should be emphasized that the relationship between the level of acceptance of the disease and the QoL domains seemed to be more significant in the controlled acromegaly subgroup where the size effect of the correlations was much bigger. The importance of perception of the illness and emotional representation of symptoms that could result in the level of acceptance affects self-perceived QoL (24,26) thus should not be ignored by health providers, rather treated as a starting point of conversation. However, biochemical normalization cannot be simply translated as lessening acromegaly burden of concomitant diseases, thus biochemical control does not equal clinical control which is more complex and multidimensional.…”

“…Intercorrelation between acromegaly, presence of depressive symptoms and satisfaction of patients was also found by Kepicoglu et al (16). This being said, psychopathology is suggested not only to be an independent factor modifying QoL (15,26,27), but also superior to biochemical control and other factors. Proper consideration of the role of psychopathology plays a major role in holistic attitude toward such patients.…”

“…This paper was aimed at detailed comparative analyzes between two groups of patients living with acromegaly differing in disease activity, and not analyzing individual variables compared to the group of healthy participants who do not have to face the consequences resulting from illness or their level of acceptance. Results on the QoL between different clinical groups and healthy participants were presented in another paper in details (26).…”

Quality of life in patients with acromegaly receiving lanreotide autogel: a real-world observational study

“…Acromegaly worsens both the physical and emotional well-being of patients, and substantially reduces quality of life (QoL) at all disease stages [2]. Patients with acromegaly have much lower scores on generic questionnaires measuring QoL compared to the general population or patients with other chronic diseases, such as asthma, angina, and osteoarthritis [3][4][5]. The physical aspect of QoL in acromegaly is substantially affected by pain, weakness, sleep problems, and limitations of daily activities [6].…”