Cytotoxicity of phenylpropanoid esters from the stems of Hibiscus taiwanensis

Cytotoxic lignans from the stems ofHelicteres hirsuta collected in indonesia

“…According to other publications, (+)-pinoresinol exhibited no cytotoxicity against the HL-60 (human leukemia cell), MCF-7 (human breast cancer) and TD47D (human breast cancer) cell lines (Mimaki et al, 1999;Umehara et al, 2004), while (−)-pinoresinol was reported to inhibit DNA synthesis (Zhuang et al, 1982). (−)-Boehmenan (4) was demonstrated to be weakly cytotoxic against the A549 (human lung cancer) and MCF-7 cell lines with ED 50 values of 18.4 and 10.9 µg/mL, respectively (Wu et al, 2004). In the present work, it also exhibited equivalent activity when tested against the Lu1, LNCaP, MCF-7 and HUVEC cell lines.…”

Anti-inflammatory Principles from the Stem and Root Barks of Citrus medica

“…(10→19)abeo-7a-acetoxy-10b-hydroxyisoobacunoic acid-3,10-lactone (16), 39) syringaresinol (17), 40) cis-p-coumaric acid (18), 41) nomilin (19) 30) and limonin (20), 35) were also isolated from the root bark of Citrus medica L. var. sarcodactylis SWINGLE.…”

Constituents from the Stems of Hibiscus taiwanensis

“…The aqueous solution was partitioned with CHCl 3 and EtOAc, successively. The obtained CHCl 3 and EtOAc soluble fractions were individually separated by silica gel column chromatography to afford fifty-six compounds, including five new compounds: hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds: hibicuwanin A (6), 3) hibicuwanin B (7), 3) (7S,8S)-demethylcarolignan E (8), 3) threo-carolignan E (9), 4) erythro-carolignan E (10), 4) threo-1-C-syringylglycerol (11), 5) 9,9Ј-O-feruloyl-(Ϫ)-secoisolaricinresinol (12), 6) dihydrodehydrodiconiferyl alcohol (13), 7) boehmenan (14), 4) (Ϫ)-syringaresinol (15), 8) cleomiscosin A (16), 9) cleomiscosin C (17), 9) mansonone E (18), 10) mansonone H (19), 11) hibiscone C (20), 12) isohemigossypol-1-methyl ether (21), 13) gossyvertin (22), 14) N-trans-feruloyltyramine (23), 15) N-cis-feruloyltyramine (24), 16) 2-(2-hydroxytricosanoylamino)-1,3,4-hexadecanetriol (25), 17) myricerol (26), 18) myriceric acid A (27), 18) myriceric acid B (28), 18) myriceric acid C (29), 18) uncarinic acid A (30), 19) uncarinic acid B (31), 19) 3-oxo-olean-12-en-28-oic acid (32), 20) scopoletin (33), 21) scoparone (34), 22) 4-hydroxybenzoic acid (35), 15) ferulic acid (36), 15) methyl trans-ferulate (37), 23) methyl cis-ferulate (38), 24) lignocerylferulate (39), 25) caffeic acid (...…”

“…These differences were believed to be due to the different configuration at C-3. 3 -3 and acetonyl groups located toward axial and equatorial positions, respectively. The condensation product of mansonone E and acetone with axial CH 3 -3 and equatorial CH 3 COCH 2 -7 was proposed to be the structure of hibiscuslide B (2).…”