Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii

Cytotoxic Terpenes from the Stems of <i>Dipterocarpus obtusifolius</i> Collected in Cambodia

“…32) A few oligomeric stilbenoids were isolated as cytotoxic constituents from Dipterocarpus genus. 1,33) The present study found that triterpenoids which are frequently occurring compounds in this genus Dipterocarpus as a chemotoxonomic marker were also present in this plant. 32) Triterpenes in this plant might also be responsible for cytotoxic activities.…”

“…and resveratrol oligomers, 1,6) and exert diverse biological activities, such as anticancer, anti-human immunodeficiency virus (HIV), 1,4,7) antibacterial, 8,9) and antioxidant activities. 9) As part of our ongoing project in search for biologically active small molecules from Cambodian medicinal plants, 10) Dipterocarpus obtusifolius TEIJSM.…”

Pyhtochemical Studies on Resveratrol from Dipterocarpus Crinitus as Damping Off Disease Agent

“…Fraction DC 3 and 4 were further purified by column chromatography and led to the isolation of 5 oligomer resveratrol: !-Viniferin (1), "-viniferine (2), Hopeaphenol (3), isohopehenol (4) and laevifonol (5). The structure of the compounds were confirmed by one and two-dimensional NMR analyses and comparison with previous data [2]. The polyphenolic compounds which are known as phytoalexin were further investigated for antioxidant and damping off disease agent.…”

Cytotoxic oligostilbenes from Shorea hopeifolia

“…We considered that (-)-hopeaphenol which was the most active compound was the main contributor in synergetic effects of the acetone extract in the increased cytotoxic activity. (-)-Hopeaphenol has also been reported to have potent cytotoxicity on the human epidermoid carcinoma of the sopharynx (Guebailia et al, 2006) and murine leukemia P-388 cells (Latip et al, 2011;Muhtadi et al, 2006;Sahidin et al, 2004). These results, also support previous studies which reported that compound 2 showed strong cytotoxic activity against rat hepatocytes (Oshima and Ueno, 1993) and murine leukemia cells P-388 (Saroyobudiono et al, 2008).…”