This paper presents the synthesis of a polypropylene nanocomposite. The
nanocomposites were characterized using different techniques: atomic electron
microscopy (AFM), surface shape was evaluated by (SEM),(EDS),(XRD) and (FTIR). The study
showed that the platinum nanocomposite had a fatal effect on both strains of bacteria
used, as well as on the growth of fungi. The compound tested showed antioxidant
properties moderate activity was found. The mentioned material were evaluated in normal
cell line HdFn (Human Dermal Fibroblasts, neonatal) and breast cancer MCF-7 cancer cell
line , by MTT assay for study cytotoxic effects, morphological changes, all experiments
were conducted on cell lines by using the materials alone. The results of the MTT assay
showed that the material [PP/ Pt] had a toxic effect on the cell lines, and the toxicity
of the materials was concentration-dependent manner where that have higher toxicity on
the MCF-7 cell lines than HdFn. The toxic effects of material alone were reflected on
cell morphology by appearance irreversible cytopathic changes in the treated cells,
which ability to cause cellular death and DNA damage. When there appeared a significant
increase in the concentration of nanocomposite , [PP/Pt] nanocomposite have an
inhibitory effect on both breast cancer and normal cell lines. Conclude both materials
have genotoxic effects on normal and cancer cell lines.