Polypropylene/Pt Nanocomposite: Synthesis, Characterization and Study the Cytotoxic Effects

Abstract

This paper presents the synthesis of a polypropylene nanocomposite. The nanocomposites were characterized using different techniques: atomic electron microscopy (AFM), surface shape was evaluated by (SEM),(EDS),(XRD) and (FTIR). The study showed that the platinum nanocomposite had a fatal effect on both strains of bacteria used, as well as on the growth of fungi. The compound tested showed antioxidant properties moderate activity was found. The mentioned material were evaluated in normal cell line HdFn (Human Dermal Fibroblasts, neonatal) and breast cancer MCF-7 cancer cell line , by MTT assay for study cytotoxic effects, morphological changes, all experiments were conducted on cell lines by using the materials alone. The results of the MTT assay showed that the material [PP/ Pt] had a toxic effect on the cell lines, and the toxicity of the materials was concentration-dependent manner where that have higher toxicity on the MCF-7 cell lines than HdFn. The toxic effects of material alone were reflected on cell morphology by appearance irreversible cytopathic changes in the treated cells, which ability to cause cellular death and DNA damage. When there appeared a significant increase in the concentration of nanocomposite , [PP/Pt] nanocomposite have an inhibitory effect on both breast cancer and normal cell lines. Conclude both materials have genotoxic effects on normal and cancer cell lines.

Studying the effect partial Ni2O3 nano-particles compensation on the properties of the compound Bi2Sr2-xYxCa2Cu3-yNiyO10+δ superconductors

“…The formation of the Bi-2223 phase is particularly sensitive to a wide range of factorsSeveral factors can influence the synthesis of materials, such as sintering temperature, thermal processing duration, synthesis environment, precursor compositions, and the incorporation of different cations and anions through doping or replacement [27,28]. From what we can see, Ni2O3 micro Particles considerably enhanced the formation of Bi-2223 phase [5][6][7][8][9][10], suggesting that they may be somewhat compensating for Cu's slowing effect [21,26].…”