Cytotoxic and Antimalarial Constituents from the Roots of Eurycoma longifolia.

Kuo, Ping Chung; Damu, Amooru G.; Lee, Kuo‐Hsiung; Wu, Tong

doi:10.1002/chin.200422186

Cited by 49 publications

(71 citation statements)

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“…[3][4][5][6][7][8][9][10][11][12] It is a popular herb used by many local races of Malaysia and mainly used as aphrodisiac, antipyretic and anti-malarial remedy. [39] Not surprisingly, Jah Hut people often use it as an aphrodisiac remedy.…”

Section: Discussionmentioning

confidence: 99%

“…This is not the only source of income, but also an extension anti-hyperglycemic, anti-malarial, antiproliferative, anti-schistosomal, anxiolytic and aphrodisiac activities are found in both in vivo and in vitro studies. [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Jah Hut people often use M. citrifolia to treat boils by topical application of leaves or fruits. This coincides with pharmacological validation, since boils (impetigo, folliculitis, furuncles, or carbuncles) are often caused by Staphylococcus aureus; M. citrifolia possess anti-bacterial properties to counter it.…”

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confidence: 99%

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Ethnobotanical study of medicinal plants used by the Jah Hut peoples in Malaysia

Lin¹

2005

Indian J Med Sci

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CONTEXT: An ethnobotanical study was carried out among the Jah Hut people who live in the central part of peninsular Malaysia. MATERIALS AND METHODS: The information on the medicinal plants was obtained from interview with a traditional medicinal man. The traditional uses and remedies were documented. The literature searches were carried out for the evaluation on the current status of investigations on these plants. RESULTS: In this study, we present 16 species of plants, which are commonly used among the Jah Hut people to cure some common diseases. DISCUSSIONS: This study is important to preserve the knowledge of medicinal plants used by Jah Hut people. The surveys of phytopharmacological literatures of these plants have great pharmacological and ethnobotanical significance.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Ethnobotanical study of medicinal plants used by the Jah Hut peoples in Malaysia

Lin¹

2005

Indian J Med Sci

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“…Kuo et al [67] found that among the isolates from the roots of Eurycoma longifolia, eurycomanone (137) and pasakbumin B (138) [68] …”

Section: Simaroubaceae Familymentioning

confidence: 99%

Antimalarial Activity of Plant Metabolites

Pan¹,

Xu²,

Shi³

et al. 2018

Preprint

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Malaria, as a major global health problem, continues to affect a large number of people each year, especially those in the developing countries. Effective drug discovery is still one of the main efforts to control malaria. As natural products are still considered as a key source for discovery and development of therapeutic agents, we have evaluated more than 2,000 plant extracts against Plasmodium falciparum. As a result, we discovered dozens of plant leads that displayed antimalarial activity. Our phytochemical study of some of these plant extracts led to identification of several potent antimalarial compounds. The prior comprehensive review article entitled "Antimalarial activity of plant metabolites" by Schwikkard and Van Heerden (2002) reported structures of plant-derived compounds with antiplasmodial activity and covered literature up to the year 2000. As a continuation of this effort, the present review covers the antimalarial compounds isolated from plants, including marine plants, reported in the literatures from 2001 to the end of 2017. During the span of the last 17 years, 175 antiplasmodial compounds were discovered from plants. These active compounds are organized in our review article according to their plant families. In addition, we also include ethnobotanical information of the antimalarial plants discussed.

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“…Certain studies report that pharmacologically, E. longifolia Jack. contains anticancer compound (Nurhanan et al 2005;Tee et al 2007), anti-bacteria (Farouk & Benafri 2007), osteoporosis therapy for men (Effendi et al 2012), cyto-toxic (Kuo et al 2003;Kuo et al 2004), aphrodisiac (Ang et al 2003;, antileukemia, anti-malaria, and dysentery (Chan et al 2005). Due to its various benefits, there has been a substantial increase in its demands for medicinal ingredients.…”

Section: E Longifoliamentioning

confidence: 99%