Cytotoxic and anti-inflammatory activities of some constituents from the floral buds ofSyringa patula

El‐Desouky, Samy K.; Gamal‐Eldeen, Amira M.

doi:10.1080/13880200902950785

Cited by 22 publications

(18 citation statements)

References 25 publications

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“…Modern pharmacological studies have shown the bioactivities of these metabolites, such as antitumor, antihypertensive, anti-oxidant, anti-inflammatory activities, and so on [5]. However, a systematic review of these studies has not been performed to date.…”

Section: Introductionmentioning

confidence: 99%

“…alashanensis [34] 72 Syripinnalignan Eroots and stems S. pinnatifolia var. alashanensis [34] 73 (7 S , 8 R )-Guaiacylglycerol-8- O -4′-sinapyl ether 9′- O - β -D-glucopyranosideleaves S. velutina [28] 74 (7 S , 8 R )-Syringylglycerol-8- O -4′-sinapyl ether 9′- O - β -D-glucopyranosideleaves S. velutina [28] 75 Pinoresinol-4- O - β -monoglycosidebarks S. reticulata [10] 76 Syringaresinol-4- O - bis - β -D-monoglucosidebarks S. reticulata [10] 77 Syringaresinol-4, 4''- O - bis - β -D-glucosidebarks S. reticulata [10] 78 Syringaresinolfloral buds, flowers and leaves S. patula , S. pubescens [3,5] 79 (+)-Medioresinol-4- O -glucosidefloral buds S. patula [5] 80 (−)-Pinoresinolroots and stems S. pinnatifolia var. alashanensis [30]…”

Section: Introductionmentioning

confidence: 99%

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Phytochemical and pharmacological progress on the genus Syringa

Yuan

et al. 2015

Chemistry Central Journal

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Genus Syringa, belonging to the Oleaceae family, consists of more than 40 plant species worldwide, of which 22 species, including 18 endemic species, are found in China. Most Syringa plants are used in making ornaments and traditional medicines, whereas some are employed for construction or economic use. Previous studies have shown that extracts of Syringa plants mainly contain iridoids, lignans, and phenylethanoids that have antitumor, antihypertensive, anti-oxidant, and anti-inflammatory activities. This study reviews phytochemical and pharmacological progress on Syringa in the recent 20 years and discusses the future research prospects to provide a reference in further promotion and application of the genus.Graphical AbstractPhytochemical and pharmacological progress on the genus Syringa

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Phytochemical and pharmacological progress on the genus Syringa

Yuan

et al. 2015

Chemistry Central Journal

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“…This shows that the plant extract may hamper any of all process of inflammation and acts as an anti-inflammatory agent. The anti-inflammatory potential of medicinal plants has been reported in plants Solanumnigrum [22], Phyllanthus amarus [29], Syringa patula [30], Plumeria acuminate [31] and Pistia stratiotes [32]. There are few references with respect to the anti-inflammatory activity of M. zapota.…”

Section: Discussionmentioning

confidence: 99%

Anti-Inflammatory Activity of Manilkara Zapota Leaf Extract

Konuku

Karri

Gopalakrishnan

et al. 2017

Int J Curr Pharm Sci

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Objective: Manilkara zapota is a medicinal plant which is native to Mexico and Central America, and widely distributed in India. Various parts of this plant are traditionally used for treatment of several diseases, including inflammation-associated ailments. The main aim of the present study is to evaluate the anti-inflammatory potential of ethyl acetate and methanolic extracts of M. zapota leaf. Methods:In vitro secretary phospholipase A2 (PLA2) and 5-Lipoxygenase (5-LOX) assays and In vivo studies using carrageenan induced rat paw edema model were performed to assess the anti-inflammatory activity of M. zapota leaf extracts. Results:In vitro studies suggest that M. zapota leaf extracts exhibited significant SPLA2 and 5-LOX inhibitory activities. In in vivo studies M. zapota leaf extracts showed dose dependent inhibition of carrageenan induced paw edema in rats. The anti-inflammatory activity of ethyl acetate leaf extract was superior to methanolic extract. Conclusion:This study concluded that ethyl acetate leaf extract of M. zapota exhibited significant anti-inflammatory activity and warranted further investigation to isolate and identify the components.

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“…[6][7][8][9] Previous phytochemical investigations regarding this genus have reported the isolation of secoiridoid glucosides, lignans, and phenolic compounds with anti-radical scavenging and cytotoxic activity. 10) However, only a few phytochemical studies on S. oblata var. dilatata have been reported.…”

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confidence: 99%

“…dilatata. The column chromatographic purification of the EtOAc-soluble fraction led to the isolation of two new secoiridoid glucosides, dilatioside A-B (1-2), along with thirteen known ones (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). The chemical structures of the isolated compounds were determined by their NMR spectroscopic data, MS, and methanolysis.…”

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confidence: 99%