Cytological Findings of Conventional Cervical Papanicolaou Smears in a Tertiary care Hospital

Saha, Kaushik; Sengupta, Moumita; Mistry, Chetna J

doi:10.15373/22778160/january2013/19

Cited by 3 publications

(7 citation statements)

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“…Other studies revealed 5,4%, 1.6%, 7.1% and 8.8% cases of bacterial vaginosis respectively. 14,16,17,22 Trichomonas vaginalis was seen in 1.5% cases in contrast to other studies where there were 3.2%, 0.7% and 0.6% cases. 17,19,20 Reactive cellular changes (1.5%) seen in our study was associated with inflammation.…”

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confidence: 76%

“…16,17 Epithelial cell abnormalities represented 0.5% cases in our study which includes LSIL, HSIL and ASCUS. Studies had shown that the prevalence of epithelial abnormalities were different in different places (1.7%, 1.8%, 10.3%, 5.6%, 1.8%, 2.0%, 1.2% and 13.6%) 5,14,[17][18][19][20][21][22] In a study done in the same hospital in 2010, epithelial cell abnormalities were seen in 1.1% cases. 23 Since then there is decrease in epithelial cell abnormalities which could be due to inclusion of pap smear as a routine screening procedure for cervical cancer.…”

Section: Discussionmentioning

confidence: 73%

“…Two studies done in India revealed 3.2% and 26.8% cases of reactive cellular changes. 17,19 This shows that interpretation of reactive cellular changes is very subjective and hence the results are variable.…”

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confidence: 99%

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Cervical pap smear- A prospective study in a tertiary hospital

et al. 2015

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Background: Cervical cancer is a leading cause of mortality and morbidity among women worldwide and most common gynaecological cancer in developing countries. Papanicolaou smear is a simple and cost effective screening test for cervical cancer. The aim of this study is to evaluate and interpret the cervical pap smear cytology in a tertiary hospital. The interpretation and reporting of the pap smear is based on 2001 Bethesda system. Materials and methods:This is a prospective study conducted in a tertiary hospital, Nepal Medical College over a period of two and a half years (January 2013 to June 2015). All cervical pap smears received in the department of Pathology in the study period were included.Results: A total of 4160 cervical pap smears were reported in the study period. Majority of the cases were Negative for Intraepithelial lesion or malignancy (87.9%). Bacterial vaginosis, atrophy and reactive cellular changes associated with inflammation were seen in 5.3%, 2.4% and 1.5% cases respectively. Epithelial cell abnormalities (0.5%) include Atypical squamous cells of undetermined significance, Low grade squamous intraepithelial lesion and High grade intraepithelial lesion. 88% of Low grade squamous intraepithelial lesion was seen in reproductive age group (20-45 years). Conclusion:Cervical cancer is the most common gynaecological cancer in the developing countries. Pap smear is the simple and cost effective screening tool to detect pre invasive cervical epithelial lesions.

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confidence: 76%

Section: Discussionmentioning

confidence: 73%

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Cervical pap smear- A prospective study in a tertiary hospital

et al. 2015

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“…Study done in Kathmandu revealed 0.3% of unsatisfactory smear, which is lower than in our study [7]. In contrast to our study, the incidence of unsatisfactory smear was quite high in the studies conducted by Patel Malignancy were 47% and 50.6% respectively, which is higher than in our study [19,20]. Low grade squamous intraepithelial lesion (LSIL) in our study was 0.63%, which is comparable to the other studies conducted by pudasaini et al, Hirachand et al and yeasmin et al respectively (0.2%, 0.15% and 0.3%) [1,7,12].…”

Section: Discussioncontrasting

confidence: 94%

Pap smear as early diagnostic tool for cervical cancer- A life saviour

Ramu

Bindu

Murthy

2018

Trop J Pathol Microbiol

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Background: Cervical cancer is a leading cause of mortality and morbidity among women globally and most common gynaecological cancer in developing countries. Papanicolaou smear study is a simple and cost effective screening test for cervical cancer. The aim of this study is to evaluate and interpret the pattern of cervical Pap smear cytology in a tertiary hospital. The interpretation and reporting of the Pap smear is based on 2001 Bethesda system. Materials and Methods: This is a retrospective study conducted at

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“…The reason may be that the study was conducted in a tertiary care hospital, which is a referral centre for symptomatic as well as clinically suspicious patients, thus more cases of positive results. 25 22 Ranabhat et al 26 20 27 28 In present study, incidence of ASC-US/SIL ratio was 0.67. The ASC-US/SIL ratio is a quality indicator of reporting quality of Pap smears and should be less than 1.5:1 for satisfactory reporting quality.…”

Section: Discussionmentioning

confidence: 48%

Cytomorphological evaluation of squamous cell abnormalities observed on cervical smears in government medical college, Jabalpur, India: a five year study

2016

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INTRODUCTIONCervical cancer is the fourth most common cancer in women and the seventh overall, with an estimated 528,000 new cases every year. Cancer cervix is the most common cancer in women in several less developed countries, and now the second most common cancer in India. Almost 70% of the global burden of cervical cancer is in areas with lower levels of development, and more than one fifth of all new cases are diagnosed in ABSTRACT Background: Cervical cancer is the fourth most common cancer affecting women worldwide, the most common cancer in women in several less developed countries, and now the second most common cancer in India. Cervical cytology by papanicolaou (PAP) smear test is an effective tool for detecting abnormal cytology in early stages, thus allowing early detection and treatment. The PAP smear is extremely important for detecting premalignant and malignant conditions of cervix. The study was conducted to determine; (1) Cytomorphologic incidence of various lesions of uterine cervix; (2) Categorization of detected lesions according to Bethesda system; (3) Determination of epithelial abnormalities by cervical cytology. Methods: The settings and design of this study is a hospital based prospective study from a tertiary care centre in Central India. A total of 5813 conventional pap smear tests collected from January 2010 and December 2014 were analyzed. All patients attending outpatient department of obstetrics and gynecology for complaints of abnormal cervical discharge, dyspareunia, inter-menstrual bleeding, post-coital bleeding and lower abdominal pain were included. Various cervical pap screening camps were also done during this period. Smears were fixed and stained with hematoxylin & eosin (H&E) and papanicolaou stain were done. Results: The overall frequency of normal, inadequate, inflammatory, and abnormal smears was 11.86%, 5.73%, 74.98% and 13.2% respectively. Atypical squamous cell carcinoma of undermined significance (ASCUS) was seen in 3.61%, squamous intraepithelial lesion (SIL) was seen in 5.36%, low grade squamous intraepithelial lesion (LSIL) was seen in 2.59% while high grade squamous intraepithelial lesion (HSIL) was seen in 2.77%. Invasive carcinoma was seen in 3.69%. The premalignant epithelial abnormalities like ASCUS, LSIL and HSIL were found to be highest in the age group of 31-50 years in our study, which correlated well with other similar studies. Conclusions: Hence we should advocate regular cervical cytology (PAP) smear study, which can help to treat cervix lesions early before the progress into cervical cancer. Early detection is the only key to saving a woman's life as the later the abnormalities are discovered; mortality, morbidity and treatment cost all increase.

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Cytological Findings of Conventional Cervical Papanicolaou Smears in a Tertiary care Hospital

Cited by 3 publications

References 2 publications

Cervical pap smear- A prospective study in a tertiary hospital

Cervical pap smear- A prospective study in a tertiary hospital

Pap smear as early diagnostic tool for cervical cancer- A life saviour

Cytomorphological evaluation of squamous cell abnormalities observed on cervical smears in government medical college, Jabalpur, India: a five year study

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