Cytologic Findings in Pigmented Melanotic Schwannoma

Azarpira, Negar; Torabineghad, Simin; Sepidbakht, Sepideh; Rakei, Mohammad; Bagheri, Mohammad Hadi

doi:10.1159/000325096

Cited by 16 publications

(6 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The intermediate grade category was introduced for melanocytic tumours with bland cytologic features that manifest signs of malignancy [3]. The initial diagnosis of melanotic schwannoma was excluded by the lack of reticulin fibers surrounding individual tumour cells [2,15]. MC feature variable degrees of melanisation, ranging from gray to charcoal-black tumours [8].…”

Section: Discussionmentioning

confidence: 99%

“…At present, there is no established consensus regarding the radiological features of MC. In general, T1 iso-to hyperintensity and iso-to hypointensity on T2-weighted sequences are reported with homogeneous enhancement following gadolinium administration [2,9,18]. However, imaging characteristics are not specific due to varying degrees of melanisation and necrosis, which may affect the MRI signal [13].…”

Section: Discussionmentioning

confidence: 99%

“…However, imaging characteristics are not specific due to varying degrees of melanisation and necrosis, which may affect the MRI signal [13]. Differential considerations include various spinal neoplasms like meningioma, schwannoma or melanoma [2,12,15,23].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Bifocal extra- and intradural melanocytoma of the spine: case report and literature review

et al. 2013

View full text Add to dashboard Cite

Intradural melanocytoma, although exceedingly rare, requires a thorough work-up to exclude malignant melanoma. With only two previous reports of multifocal melanocytoma published in the literature, standard therapy has not yet been established and complete surgical removal remains the modality of choice. Patients should be closely monitored to detect local recurrence or malignant degeneration. EBR may be considered in cases where total excision is not achievable and reduces risk of local recurrences.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Bifocal extra- and intradural melanocytoma of the spine: case report and literature review

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Inmunohistoquímicamente son reactivos para los marcadores vimentina (Figura 2C), S-100 (Figura 2D) y Leu 7. La inmunorreactividad para HMB-45 es menos frecuente, no siendo de utilidad diagnóstica, ya que este marcador está presente en el melanoma maligno (16,17) .…”

Section: Discussionunclassified

Schwannoma melanótico: Reporte de un caso y revisión de la literatura

A¹,

2012

Rev. chil. radiol.

View full text Add to dashboard Cite

Los schwannomas son lesiones neoplásicas benignas derivadas de las células de Schwann, células constituyentes de la vaina nerviosa (1). La variante menos frecuente dentro de este tipo de neoplasias es el schwannoma melanótico (2). Este puede presentarse de forma esporádica o asociado al complejo de Carney (3). El diagnóstico de esta entidad reviste complejidad debido al diagnóstico diferencial con tumores malignos, especialmente el melanoma metastásico, teniendo este último un pronóstico y tratamiento radicalmente distinto (4). Este último, a diferencia del schwannoma, sigue un curso maligno, requiriendo resección amplia para evitar la recurrencia local y eventual potencial metastásico (5). Presentamos aquí un caso clínico de schwannoma melanótico, incluyendo una extensa revisión de la literatura sobre este tema. Caso clínico Mujer de 60 años con antecedentes de una parálisis facial derecha antigua y una trombosis de la vena central de la retina del ojo izquierdo. Entre otros antecedentes presenta hipertensión, dislipidemia y obesidad. Sin antecedentes familiares de importancia. Consulta por un cuadro de aproximadamente un año de evolución de paresia e hipoestesia en extremidades inferiores, mayor a derecha, progresando a extremidades superiores. Un mes previo al ingreso evoluciona con una importante limitación de la marcha

show abstract

“…Nuclear pseudoinclusions were noted in some cases. [2][3][4][5][6][7][8][9][10][11][12] However, mitotic activity was generally low, which could be a helpful diagnostic clue in the differential diagnosis with malignant melanoma.…”

Section: Introductionmentioning

confidence: 99%

Fine‐needle aspiration cytology of melanotic schwannoma in the submandibular gland

Huang

et al. 2020

Diagnostic Cytopathology

View full text Add to dashboard Cite

Cytologic Findings in Pigmented Melanotic Schwannoma

Cited by 16 publications

References 12 publications

Bifocal extra- and intradural melanocytoma of the spine: case report and literature review

Bifocal extra- and intradural melanocytoma of the spine: case report and literature review

Schwannoma melanótico: Reporte de un caso y revisión de la literatura

Fine‐needle aspiration cytology of melanotic schwannoma in the submandibular gland

Contact Info

Product

Resources

About