Cytologic demonstration of ?dysplastic? follicular dendritic cells in a case of hyaline-vascular Castleman's disease

Taylor, Graeme; Smeeton, Ian W.M.I.

doi:10.1002/(sici)1097-0339(200004)22:4<230::aid-dc6>3.0.co;2-5

Cited by 28 publications

(27 citation statements)

References 20 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the latter findings, Castleman's disease should be included in the differential diagnosis, and the invariably increasing branching hyaline capillary fragments should at least raise this diagnostic possibility. Although atypical follicular dendritic cells are thought to be diagnostic of Castleman's disease [7], they are not consistently found on FNA of lymph node [69]. Therefore, FNA is not recommended for the diagnosis of Castleman's disease [69], and a definite diagnosis will require biopsy, tissue examination, and immunophenotyping.…”

Section: Hematolymphoid Pathologymentioning

confidence: 99%

“…HIV-infected patients have disproportionately high rates of infection with oncogenic viruses, such as human papillomavirus (HPV), Kaposi sarcoma human virus/human herpesvirus-8 (KSHV/HHV-8), and Epstein-Barr virus (EBV). HPV is closely linked to anogenital cancer [2–4] and HHV-8 associated malignancies include KS [5], primary effusion lymphoma (PEL) [6], and multicentric Castleman's disease [7]. Finally, EBV infection has been linked to Hodgkin's lymphoma [8], plasmablastic lymphoma (PBL) [9], and leiomyosarcoma [10].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Review of HIV-Related Cytopathology

Lang

Khalbuss

Michelow

et al. 2011

Pathology Research International

View full text Add to dashboard Cite

Exfoliative and aspiration cytologies play a major role in the management of patients with human immunodeficiency virus infection. Common cytology samples include cervicovaginal and anal Papanicolaou tests, fine needle aspirations, respiratory specimens, body fluids, Tzanck preparations, and touch preparations from brain specimens. While the cytopathologists need to be aware of specific infections and neoplasms likely to be encountered in this setting, they should be aware of the current shift in the pattern of human immunodeficiency virus-related diseases, as human immunodeficiency virus patients are living longer with highly active antiretroviral therapy and suffering fewer opportunistic infections with better antimicrobial prophylaxis. There is a rise in nonhuman immunodeficiency virus-defining cancers (e.g., anal cancer, Hodgkin's lymphoma) and entities (e.g., gynecomastia) from drug-related side effects. Given that fine needle aspiration is a valuable, noninvasive, and cost-effective tool, it is frequently employed in the evaluation and diagnosis of human immunodeficiency virus-related diseases. Anal Papanicolaou tests are also increasing as a result of enhanced screening of human immunodeficiency virus-positive patients for cancer. This paper covers the broad spectrum of disease entities likely to be encountered with human immunodeficiency virus-related cytopathology.

show abstract

Section: Hematolymphoid Pathologymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Review of HIV-Related Cytopathology

Lang

Khalbuss

Michelow

et al. 2011

Pathology Research International

View full text Add to dashboard Cite

show abstract

“…Awareness of the presence of dysplastic follicular dendritic cells within aspirates of CD will result in less cytological confusion in the future and may help to avoid the possibility of misdiagnosing Hodgkin’s lymphoma which has certain cytological similarities. [4] In the appropriate clinical context, a mature small lymphoid population associated with larger atypical cells which are consistent with follicular dendritic cells can be suggestive of CD. [5] However, we did not identify these dysplastic follicular dendritic cells, cells with crumpled tissue paper appearance and Reed Sternberg-like cells in our aspirates.…”

Section: Discussionmentioning

confidence: 99%

Cytologic picture of Castleman′s disease: A report of two cases

Sudha

Vivekanand

2010

J Cytol

View full text Add to dashboard Cite

Castleman’s disease (CD), also called giant lymph nodal hyperplasia, is a lymphoproliferative disorder secondary to lymphoid follicle hyperplasia and marked capillary proliferation with endothelial hyperplasia. It presents as enlarged lymph nodes in the mediastinum, neck, groin, axilla and other sites. On clinical examination as well as gross examination, this disease mimics lymphomas and tuberculosis. Since cytological appearances vary depending on the type and extent of hyperplasia, fine needle aspiration cytology (FNAC) findings may not always be conclusive in all cases. We studied aspirates in two cases of CD, one of which presented with multiple enlarged axillary lymph nodes and the other with enlarged cervical lymph node. Cytology revealed reactive lymphadenitis with hyalinized capillaries and other features. Lymph node excision in both cases confirmed the diagnosis.

show abstract

“…Sometimes, occasional follicular dendritic cells may appear atypical and can be mistaken as Reed-Sternberg cells on cytologic examination. 37,38 Tingible-body macrophages are rarely identified. Markedly pleomorphic cells with high mitotic activity are not seen.…”

Section: Castleman's Diseasementioning

confidence: 99%

Mediastinum

Ng¹

2008

Comprehensive Cytopathology

View full text Add to dashboard Cite

Cytologic demonstration of ?dysplastic? follicular dendritic cells in a case of hyaline-vascular Castleman's disease

Cited by 28 publications

References 20 publications

Review of HIV-Related Cytopathology

Review of HIV-Related Cytopathology

Cytologic picture of Castleman′s disease: A report of two cases

Mediastinum

Contact Info

Product

Resources

About