Cytokines, adipocytokines and inflammatory markers in patients on continuous ambulatory peritoneal dialysis and hemodialysis

Abstract

We can conclude that cytokine production is more obvious in HD process.

Association between baseline serum hepcidin levels and infection in kidney transplant recipients: Potential role for iron overload

“…Supporting this, we found higher serum levels among patients receiving pre-transplant hemodialysis compared with those on peritoneal dialysis. Some authors have observed differences in concentrations of proinflammatory cytokines (such as tumor necrosis factorα or IL-6) according to the dialysis modality,51 although discordant results have been also reported 52. In our…”

“…Supporting this, we found higher serum levels among patients receiving pre‐transplant hemodialysis compared with those on peritoneal dialysis. Some authors have observed differences in concentrations of proinflammatory cytokines (such as tumor necrosis factor‐α or IL‐6) according to the dialysis modality, although discordant results have been also reported . In our opinion, these lines of reasoning (elevated hepcidin‐25 levels due to either iron overload or maintained inflammatory response) should be regarded as complementary rather than mutually exclusive, since both conditions may synergistically interact to increase the infection risk.…”

The Benefit of Anti-Inflammatory and Renal-Protective Dietary Ingredients on the Biological Processes of Aging in the Kidney

“…Also, healthy aging adults have higher circulating levels of cytokines including IL-6, IL-8, IL-10, and TNF-α [53]. Several of these circulating cytokines including TNF-α and IL-6 are higher in patients with chronic renal failure [54,55] and this can occur even in the absence of aging. It is conceivable that indicating higher levels of circulating cytokines in aging can affect kidney function.…”

Successful Peritoneal Dialysis for the Treatment of Inotrope-Dependent End-Stage Heart Failure

“…The use of the peritoneal membrane in PD may remove inflammation-inducing substances much more effectively compared to the dialyzer membrane in hemodialysis. 22) Indeed, Oncel, et al demonstrated that the serum TNF-α and IL-6 levels of patients on continuous ambulatory PD were significantly lower than with hemodialysis. 22) In addition, the use of an icodextrin-containing PD solution may have had favorable effects on the uremic milieu and metabolic control and thus, the cardiac hemodynamics in the present study.…”

“…22) Indeed, Oncel, et al demonstrated that the serum TNF-α and IL-6 levels of patients on continuous ambulatory PD were significantly lower than with hemodialysis. 22) In addition, the use of an icodextrin-containing PD solution may have had favorable effects on the uremic milieu and metabolic control and thus, the cardiac hemodynamics in the present study. 12) Meanwhile, it should be noted that patients with poor comprehensive understanding and management abilities for daily PD procedure are not suitable for home-based chronic PD.…”